Breast
| Primary Site | Histology | 
|---|---|
| C500-C506, C508-C509 | 8000-8700, 8982-8983 | 
| C501-C506, C508-C509 | 8720-8790 | 
Notes
8000-8700, 8720-8790 [except C500], 8982-8983 C500 Nipple C501 Central portion of breast C502 Upper-inner quadrant of breast C503 Lower-inner quadrant of breast C504 Upper-outer quadrant of breast C505 Lower-outer quadrant of breast C506 Axillary Tail of breast C508 Overlapping lesion of breast C509 Breast, NOS **Note 1:** The following sources were used in the development of this schema * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 48 *Breast*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** See the following schemas for the listed histologies * 8720-8790: *Melanoma Skin* (C500 only) * 8710-8714, 8800-8803, 8810-8921, 8932-8934, 8940-8981, 8990, 9000-9016, 9030-9043, 9045-9138, 9141-9230, 9240-9580, 9582: *Soft Tissue Trunk and Extremities* * 8804-8806, 8930-8931, 8991, 9020, 9044, 9231, 9581: *Soft Tissue Rare* * 8935-8936: *GIST* * 8992: *Soft Tissue Other* * 9140: *Kaposi Sarcoma* * 9700-9701: *Mycosis Fungoides* **Note 3:** In addition to coding *EOD Primary Tumor, EOD Regional Nodes* and *EOD Mets*, the following data items are also needed to assign a stage group for Breast. * ER Summary * PR Summary * HER2 Summary * Oncotype Dx Recurrence ScoreData Items
| Name | Default Value | Used in Derivation | NAACCR Item | Required By | Metadata | 
|---|---|---|---|---|---|
| Year of Diagnosis | No | 
                    NAACCR #390
                    
                         dateOfDiagnosis  | 
            
            
                None | ||
| Primary Site | Yes | 
                    NAACCR #400
                    
                         primarySite  | 
            
            
                None | ||
| Histology | Yes | 
                    NAACCR #522
                    
                         histologicTypeIcdO3  | 
            
            
                None | ||
| Behavior | Yes | 
                    NAACCR #523
                    
                         behaviorCodeIcdO3  | 
            
            
                None | ||
| Tumor Size Clinical | No | 
                    NAACCR #752
                    
                         tumorSizeClinical  | 
            
            
                None | ||
| Tumor Size Pathological | No | 
                    NAACCR #754
                    
                         tumorSizePathologic  | 
            
            
                None | ||
| Tumor Size Summary | 999 | Yes | 
                    NAACCR #756
                    
                         tumorSizeSummary  | 
            
            
                None | |
| Regional Nodes Positive | 99 | No | 
                    NAACCR #820
                    
                         regionalNodesPositive  | 
            
            
                None | |
| Regional Nodes Examined | 99 | No | 
                    NAACCR #830
                    
                         regionalNodesExamined  | 
            
            
                None | |
| Sentinel Lymph Nodes Positive | 99 | No | 
                    NAACCR #835
                    
                         sentinelLymphNodesPositive  | 
            
            
                None | |
| Sentinel Lymph Nodes Examined | 99 | No | 
                    NAACCR #834
                    
                         sentinelLymphNodesExamined  | 
            
            
                None | |
| LVI | 9 | No | 
                    NAACCR #1182
                    
                         lymphVascularInvasion  | 
            
            
                None | |
| RX Summ Surgery/Radiation Sequence | No | 
                    NAACCR #1380
                    
                         rxSummSurgRadSeq  | 
            
            
                None | ||
| RX Summ Systemic/Surgery Sequence | No | 
                    NAACCR #1639
                    
                         rxSummSystemicSurSeq  | 
            
            
                None | ||
| EOD Primary Tumor | 999 | Yes | 
                    NAACCR #772
                    
                         eodPrimaryTumor  | 
            
            
                None | |
| EOD Regional Nodes | 999 | Yes | 
                    NAACCR #774
                    
                         eodRegionalNodes  | 
            
            
                None | |
| EOD Mets | 00 | Yes | 
                    NAACCR #776
                    
                         eodMets  | 
            
            
                None | |
| SS2018 | No | 
                    NAACCR #764
                    
                         summaryStage2018  | 
            
            
                None | ||
| Grade Clinical | 9 | Yes | 
                    NAACCR #3843
                    
                         gradeClinical  | 
            
            
                All | SSDI | 
| Grade Pathological | 9 | Yes | 
                    NAACCR #3844
                    
                         gradePathological  | 
            
            
                All | SSDI | 
| Grade Post Therapy Clin (yc) | Yes | 
                    NAACCR #1068
                    
                         gradePostTherapyClin  | 
            
            
                All | SSDI | |
| Grade Post Therapy Path (yp) | Yes | 
                    NAACCR #3845
                    
                         gradePostTherapy  | 
            
            
                All | SSDI | |
| Lymph Nodes Positive Axillary Level I-II | X8 | Yes | 
                    NAACCR #3882
                    
                         lnPositiveAxillaryLevel1To2  | 
            
            
                All | SSDI | 
| ER Summary | 9 | Yes | 
                    NAACCR #3827
                    
                         estrogenReceptorSummary  | 
            
            
                All | SSDI | 
| ER Percent Positive | XX8 | No | 
                    NAACCR #3826
                    
                         estrogenReceptorPercntPosOrRange  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| ER Allred Score | X8 | No | 
                    NAACCR #3828
                    
                         estrogenReceptorTotalAllredScore  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| PR Summary | 9 | Yes | 
                    NAACCR #3915
                    
                         progesteroneRecepSummary  | 
            
            
                All | SSDI | 
| PR Percent Positive | XX8 | No | 
                    NAACCR #3914
                    
                         progesteroneRecepPrcntPosOrRange  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| PR Allred Score | X8 | No | 
                    NAACCR #3916
                    
                         progesteroneRecepTotalAllredScor  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| HER2 Overall Summary | 9 | Yes | 
                    NAACCR #3855
                    
                         her2OverallSummary  | 
            
            
                All | SSDI | 
| HER2 IHC Summary | 8 | No | 
                    NAACCR #3850
                    
                         her2IhcSummary  | 
            
            
                CCCR/Canada 2018–2020 COC 2018–2020 SEER (RC) 2018–2020  | 
            
            SSDI | 
| HER2 ISH Summary | 8 | No | 
                    NAACCR #3854
                    
                         her2IshSummary  | 
            
            
                CCCR/Canada 2018–2020 COC 2018–2020 SEER (RC) 2018–2020  | 
            
            SSDI | 
| HER2 ISH DP Ratio | XX.8 | No | 
                    NAACCR #3852
                    
                         her2IshDualProbeRatio  | 
            
            
                COC 2018–2020 SEER (RC) 2018–2020  | 
            
            SSDI | 
| HER2 ISH DP Copy No | XX.8 | No | 
                    NAACCR #3851
                    
                         her2IshDualProbeCopyNumber  | 
            
            
                COC 2018–2020 SEER (RC) 2018–2020  | 
            
            SSDI | 
| HER2 ISH SP Copy No | XX.8 | No | 
                    NAACCR #3853
                    
                         her2IshSingleProbeCopyNumber  | 
            
            
                COC 2018–2020 SEER (RC) 2018–2020  | 
            
            SSDI | 
| Ki-67 (MIB-1) | XXX.8 | No | 
                    NAACCR #3863
                    
                         ki67  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| Oncotype DX Recur Score - Invasive | XX9 | Yes | 
                    NAACCR #3904
                    
                         oncotypeDxRecurrenceScoreInvasiv  | 
            
            
                All | SSDI | 
| Oncotype Dx Risk Level - Invasive | 8 | No | 
                    NAACCR #3906
                    
                         oncotypeDxRiskLevelInvasive  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| Oncotype DX Recur Score - DCIS | XX8 | No | 
                    NAACCR #3903
                    
                         oncotypeDxRecurrenceScoreDcis  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| Oncotype Dx Risk Level - DCIS | 8 | No | 
                    NAACCR #3905
                    
                         oncotypeDxRiskLevelDcis  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
| Multigene Signature Method | 8 | No | 
                    NAACCR #3894
                    
                         multigeneSignatureMethod  | 
            
            
                COC SEER  | 
            
            SSDI | 
| Multigene Signature Result | X8 | No | 
                    NAACCR #3895
                    
                         multigeneSignatureResults  | 
            
            
                COC SEER  | 
            
            SSDI | 
| Response Neoadjuv Therapy | 8 | No | 
                    NAACCR #3922
                    
                         responseToNeoadjuvantTherapy  | 
            
            
                COC SEER (RC)  | 
            
            SSDI | 
Initial Context
Outputs
| Name | Default Value | Description | NAACCR Item | Metadata | 
|---|---|---|---|---|
| Schema ID | 00480 | 
                    NAACCR #3800
                    
                         schemaId  | 
            
            None | |
| Derived Version | {{ctx_alg_version}} | None | None | |
| Derived Summary Stage 2018 | 9 | 
                    NAACCR #762
                    
                         derivedSummaryStage2018  | 
            
            None |