Pathologic T

This input is used for staging


**Note 1:** Assign 88 for in situ cases (behavior code /2). TNM does not include an in situ category for NET rectum tumors. **Note 2:** Ignore intraluminal extension to adjacent segment(s) of colon/rectum or to the ileum from the cecum; code depth of invasion or extracolonic spread as indicated. **Note 3:** Tumor size must be known to assign a value of T1 or T2. You may use a physician’s statement of the T (sub)category if this is the only information in the medical record. * If the tumor appears to be in the T1 or T2 (sub)categories, but no size or category is specified, assign TX **Note 4:** Assign the appropriate T (sub)category (T1, T2) based on the tumor size for the following descriptions: Invasive tumor confined to mucosa, NOS including intramucosal, NOS Invades lamina propria, including lamina propria in the stalk of a polyp Invades submucosa (superficial invasion), including submucosa in the stalk of a polyp Confined to and not through the muscularis mucosae, including muscularis mucosae in the stalk of a polyp Confined to colon, NOS Localized, NOS **Note 5:** Assign T4 for tumor with macroscopic adhesions to other organs or structures and for pathologically confirmed tumor in adhesions. * If no tumor is present in adhesions upon microscopic examination, assign the appropriate T category to describe the microscopically confirmed depth of tumor invasion for these cases


Pathologic T Pathologic T Display Description Registrar Notes
pX pTX Primary tumor cannot be assessed Pathologic classification criteria met, evaluation done:
Physician unable to assess T
Surgical resection of primary tumor, extension not stated
Tumor size (TS) unknown for T categories where TS needed to determine T
Physician assigns pTX, no other information available to determine T
p0 pT0 No evidence of primary tumor
p1 pT1 Tumor invades lamina propria or submucosa and is no greater than 2 cm in size Note: T1 has subcategories of T1a and T1b. Assign T1 only when there is no information available to assign one of the subcategories

Stated as T1 [NOS]
p1A pT1a Tumor less than 1 cm in size Stated as T1a
p1B pT1b Tumor 1-2 cm in size Stated as T1b
p2 pT2 Tumor invades muscularis propria OR

Is greater than 2 cm in size
Muscularis propria invaded

Stated as T2
p3 pT3 Tumor invades subserosa, or non-peritonealized pericolic or perirectal tissues Extension through wall,​ NOS
Invasion through muscularis propria or muscularis,​ NOS
Perimuscular tissue invaded
Subserosal tissue/(sub)serosal fat invaded
Transmural,​ NOS

For rectum (C209):
Tumor invading through muscularis propria with intraluminal extension to colon and/or anal canal/anus

Adjacent (connective) tissue:
For all sites:
Perirectal fat
For rectosigmoid (C199):
Mesentery (including mesenteric fat,​ mesocolon)
Pericolic fat
For rectum (C209):
Rectovaginal septum

Fat,​ NOS

Stated as T3
p4 pT4 Tumor perforates peritoneum OR

Invades other organs
Invasion of/through serosa (mesothelium) (visceral peritoneum)

Adherent to other organs or structures, NOS

For both rectum and rectosigmoid sites:
Cul de sac (rectouterine pouch)
Pelvic wall/pelvic plexuses
Skeletal muscle of pelvic floor

For rectosigmoid (C199):
Small intestine
Colon via serosa
Fallopian tube(s)

For rectum (C209):
Anal canal/anus extraluminally
Bone(s) of pelvis
Ductus deferens
Perineum,​ perianal skin
Rectovesical fascia for males only
Sacral plexus
Seminal vesicle(s)

Further contiguous extension

Stated as T4
88 88 Not applicable In situ case but no pTis is defined by TNM
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Pathologic classification criteria not met
Pathologic classification criteria met, evaluation done:
Results not documented in patient record
No surgical resection of known primary tumor (not T0)
Resection insufficient for site-specific pathologic assessment
No surgical resection of primary tumor and there isn’t a positive biopsy of a structure in the highest T category and highest N category
Evidence of metastatic disease (pM1), no other workup
Only Pathologic Stage Group documented (no T, N, or M information available)