Clinical M

This input is used for staging

Notes

**Note 1:** For this schema, code all lymph node (regional and distant) involvement in regional lymph nodes (N). Only visceral and bone marrow involvement are coded in M (distant metastasis). * Peripheral blood involvement is coded in **Site-Specific Factor 1, Peripheral Blood Involvement** **Note 2:** Visceral involvement is metastatic and needs to be questioned in the absence of node or blood involvement. **Note 3:** For visceral disease (Stage IVB), documentation of involvement by only one organ outside the skin, nodes, or blood is needed. **Note 4:** Visceral involvement must be pathologically confirmed, except for the liver and spleen, which may be documented with only imaging.

NAACCR Item

NAACCR #960
Clinical M Clinical M Display Description Registrar Notes
c0 cM0 No visceral organ involvement Clinical confirmation only of visceral (non-cutaneous, extra nodal) involvement

Carcinomatosis, unknown if clinical or pathologic confirmation

Unknown; distant metastasis not stated
Distant metastasis cannot be assessed
Not documented in patient record
c1 cM1 Visceral organ involvement (must have pathology confirmation) CLINICAL assessment only:
Imaging confirmation of liver and/or spleen metastasis
Involvement of Bone marrow

Visceral (non-cutaneous, extranodal) involvement, pathologically confirmed:
Involvement by at least one organ outside the skin, nodes, blood, or bone marrow

Distant metastasis, NOS

Stated as M1
p1 pM1 Visceral organ involvement (must have pathology confirmation) HISTOLOGICALLY confirmed:
Imaging confirmation of liver and/or spleen metastasis
Involvement of Bone marrow

Visceral (non-cutaneous, extranodal) involvement, pathologically confirmed:
Involvement by at least one organ outside the skin, nodes, blood, or bone marrow

Distant metastasis, NOS
88 88 Not applicable In situ case but no pTis is defined by EORTC
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Clinical classification criteria not met
Clinical classification criteria met, evaluation done:
No information about diagnostic workup
Results not documented in patient record
Clinical evaluation of T and N not done, no evidence metastatic disease
Tumor first detected on surgical resection (no clinical workup)
Only Clinical Stage Group documented (no T, N, or M information available)