Pediatric Primary Tumor

Notes

**Note 1:** The tentorium cerebelli is an extension of the dura mater that separates the cerebellum from the inferior portion of the occipital lobes. The location of the tumor above or below the tentorium can help in determining the type of tumor; also, most adult brain tumors are supratentorial, and most pediatric brain tumors are infratentorial. In the following list, note that ICD-O-3 codes C710 and C719 include both supratentorial and infratentorial subsites. * The following subsites are **Infratentorial** - All subsites for codes C716-C717 - Hypothalamus (C710) - Pallium (C710) - Posterior cranial fossa (C719) - Thalamus (C710) * The following subsites are **Supratentorial** - All subsites for codes C711-C715 - Primary site C710 (excluding hypothalamus, pallium, thalamus) - Anterior cranial fossa (C719) - Corpus callosum (C718) - Middle cranial fossa (C719) - Tapetum (C718) - Suprasellar (C719) **Note 2:** Benign (/0) or Borderline (/1) tumors **are always coded to 050** regardless of size or extension to adjacent sites **Note 3:** A midline shift is not the same thing as crossing the midline (code 500). * Documentation must state “crosses the midline” **Note 4:** Discontiguous spread, or "drop metastasis" are coded in Pediatric Mets.

Default

999

NAACCR Item

NAACCR #9623

Code	Description
050	Benign or borderline brain
100	Brain (C700, C710-C719) Infratentorial tumor confined to * Brain stem or meninges of brain stem (one side) - Medulla oblongata - Midbrain (mesencephalon) - Pons * Cerebellum or meninges of cerebellum (one side or midline) - Lateral lobes - Median lobe of cerebellum - Vermis * Hypothalamus * Pallium * Thalamus Infratentorial tumor * Both cerebellum and brain stem involved with tumor on one side Supratentorial tumor confined to * Cerebral hemisphere (cerebrum) or meninges of cerebral hemisphere (one side) - Frontal lobe - Occipital lobe - Parietal lobe - Temporal lobe Confined to ventricles Tumor invades or encroaches upon ventricular system Confined to brain, NOS Confined to meninges, NOS
200	CNS Other (C701, C709, C720-C729) Confined to tissue or site of origin Localized, NOS
500	Brain (C700, C710-C719) Tumor crosses the midline Tumor invades * Bone (skull) (see code 700 for other bone involvement) * Contralateral hemisphere * Corpus callosum (including splenium) * Major blood vessel(s) * Meninges (e.g., dura) * Nerves (cranial, NOS) * Spinal cord/canal Supratentorial tumor extends infratentorially to involve * Brain stem * Cerebellum * Hypothalamus * Pallium * Posterior cranial fossa * Thalamus Infratentorial tumor extends supratentorially to involve * Anterior cranial fossa * Cerebrum (cerebral hemisphere) (excluding hypothalamus, pallium, thalamus) (see code 100 for hypothalamus, pallium, thalamus) * Middle cranial fossa * Suprasellar brain * Tapetum
600	CNS Other (C701, C709, C720-C729) Adjacent connective/soft tissue Adjacent muscle Bone (skull) (see code 700 for other bone involvement) Brain for cranial nerve tumor(s) (see code 700 for sites other than cranial nerve tumors) Major blood vessel(s) Meningeal tumor infiltrates nerve Nerve tumor infiltrates meninges (dura) Sphenoid and frontal sinuses (skull)
700	Brain (C700, C710-C719) Circulating cells in cerebral spinal fluid (CSF) Bone other than Skull (see code 500 for skull) Nasal cavity Nasopharynx Other direct extension outside CNS Posterior pharynx Further contiguous extension
750	CNS Other (C701, C709, C720-C729) Bone other than skull (see code 400 for skull) Brain except for cranial nerve tumor(s) (see code 600 for cranial nerve tumors) Eye Further contiguous extension
800	No evidence of primary tumor
999	Unknown; extension not stated Primary tumor cannot be assessed Not documented in medical record Death Certificate Only

(1) American Society of Clinical Oncology © 2009, The International Neuroblastoma Risk Group (INRG) Classification System: AN INRG Task Force Report; published by American Society of Clinical Oncology, 2009 (2) Aitken JF, Youlden D, O’Neill L, Gupta S, Frazier AL, eds. Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines – Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.