International Neuroblastoma Pathology Prognostic Classification (INPC)
Shimada Classification, Unfavorable histology or Favorable histology
Notes
**Note 1:** This SSDI is effective for diagnosis years 2024+
* For cases diagnosed 2018-2023, leave this SSDI blank
**Note 2:** The International Neuroblastoma Pathology Prognostic Classification (INPC) (unfavorable versus favorable histology) is a biologically relevant classification based on morphologic features of neuroblastic tumors which has prognostic indications. It is based on the following criteria
* Age
* Neuroblastic maturation
* Schwannian stromal content
* Mitosis-kayorrhexis index (MKI)
* Degree of differentiation (grade)
**Note 3:** The INPC results are to be coded based on either biopsy or surgical resection (without neoadjuvant therapy). If the only results are from a post neoadjuvant surgical resection, code 9.
**Note 4:** Physician statement of unfavorable vs favorable histology can be used to code this data item when no other information is available, provided there is information that the results are from a biopsy or surgical resection without neoadjuvant therapy.
Metadata
SSDI
| Code |
Description |
| 0 |
Unfavorable |
| 1 |
Favorable |
| 7 |
Test ordered, results not in chart |
| 8 |
Not applicable: Information not collected for this case
(If this information is required by your standard setter, use of code 8 may result in an edit error) |
| 9 |
Not documented in medical record
Cannot be determined by pathologist
International Neuroblastoma Pathology Prognostic Classification (INPC) not assessed or unknown if assessed
INPC assessed only at post neoadjuvant surgical resection |
| <BLANK> |
N/A - Diagnosis year is prior to 2024 |
(1) American Society of Clinical Oncology © 2009, The International Neuroblastoma Risk Group (INRG) Classification System: AN INRG Task Force Report; published by American Society of Clinical Oncology, 2009
