Pediatric Mets

This input is used for staging

M Category

Notes

**Note 1:** The following resources can be used to find information on CNS involvement: imaging, laboratory reports, CSF lactate dehydrogenase (LD, LDH) test **Note 2:** Code 00 for benign (behavior /0) and borderline (behavior /1) tumors. **Note 3:** Use code 70 when the only information is “distant metastasis, NOS,” and there is no documentation regarding the specific metastases. * If there are specific metastasis documented that are not listed in codes 15, 25, or 35, or 45, assign code 45 for “other specified distant metastasis.”

Default

NAACCR Item

NAACCR #9625

Code	Description
00	No visible disease on imaging (MRI brain and spine) beyond primary site of disease AND no tumor cells into the cerebrospinal fluid (CSF)
15	Tumor cells in the CSF * Circulating cells in cerebral spinal fluid (CSF)
25	Visible metastasis in brain * Adjacent connective/soft tissue * Adjacent muscle * Bone * Major blood vessel(s) * Meninges (e.g., dura) * Multiple/multifocal tumors * Nerves (cranial, NOS) * Ventricular system
35	Visible metastasis in spine OR Visible metastasis in cervicomedullary (junction)
45	Metastasis outside of the central system Other specified distant metastasis
70	Distant metastasis, NOS
99	Unknown; distant metastasis not stated Not documented in medical record Death Certificate Only

(1) Aitken JF, Youlden D, O’Neill L, Gupta S, Frazier AL, eds. Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines – Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.