NAACCR Item #3910: Peripheral Blood Involvement

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3910 1 NAACCR 2018 18

NAACCR XML: Tumor.peripheralBloodInvolvement

Description
Peripheral blood involvement, summarized in "B category", refers to the percentage of peripheral blood lymphocytes that are atypical (Sezary) cells and whether they are "Clone negative" or "Clone positive".
Rationale
Peripheral blood involvement is a prognostic factor required in AJCC 8th edition, Chapter 81 Primary Cutaneous Lymphomas, for staging of Mycosis Fungoides and Sezary Syndrome. It was previously collected as Mycosis Fungoides, CS SSF #1.
Codes
0Absence of significant blood involvement
5% or less of peripheral blood lymphocytes are atypical (Sezary) cells
Clone unknown
Stated as B0
1Absence of significant blood involvement
5% or less of peripheral blood lymphocytes are atypical (Sezary) cells
Clone negative
Stated as B0a
2Absence of significant blood involvement:
5% or less of peripheral blood lymphocytes are atypical (Sezary) cells
Clone positive
Stated as B0b
3Low blood tumor burden
More than 5% of peripheral blood lymphocytes are atypical (Sezary) cells but does not meet the criteria of B2
Clone unknown
Stated as B1
4Low blood tumor burden
More than 5% of peripheral blood lymphocytes are atypical (Sezary) cells but does not meet the criteria of B2
Clone negative
Stated as B1a
5Low blood tumor burden
More than 5% of peripheral blood lymphocytes are atypical (Sezary) cells but does not meet the criteria of B2
Clone positive
Stated as B1b
6High blood tumor burden
Greater than or equal to 1000 Sezary cells per microliter (uL)
Clone positive
Stated as B2
7Test ordered, results not in chart
9Not documented in medical record
Peripheral Blood Involvement not assessed or unknown if assessed
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.