EOD Primary Tumor

Notes

**Note 1:** Over 90% of penile cancers are squamous cell carcinomas arising in the skin. Other cancers arising in the skin include adenocarcinomas (5%) arising in sweat glands, melanomas (2%, included in the Melanoma schema), and basal cell carcinoma (2%). About 1% of penile cancers are sarcomas, arising in subcutaneous connective tissues. **Note 2:** If verrucous carcinoma (8051/3) is described as noninvasive or as having a broad pushing border or penetration, assign code 050. If verrucous carcinoma is not so characterized, assign code 070, Verrucous carcinoma, NOS. If there is destructive invasion of verrucous carcinoma into structures in code 100 or greater, assign the appropriate higher code. **Note 3:** Tumors limited to the penis (see codes 100, 200, 300) include * Dartos fascia (foreskin) * Dermis (foreskin) * Lamina propria (glans and foreskin) * Subepithelial connective tissue (shaft)
Code Description SS2018 T
000 In situ, intraepidermal, intraepithelial, noninvasive Bowen disease Carcinoma in situ (Penile intraepithelial neoplasia III [PeIN III]) Erythroplasia of Queyrat IS
050 Noninvasive localized squamous cell carcinoma Noninvasive verrucous carcinoma IS
070 Verrucous carcinoma, NOS (ICD-O-3 code 8051/3 only) L
100 Limited to penis - WITHOUT perineural and/or lymphovascular invasion - WITH low grade (i.e., grade 1-2) or UNKNOWN grade L
150 Code 100 with high grade (i.e., grade 3 or sarcomatoid) L
200 Limited to penis - WITH perineural and/or lymphovascular invasion - WITH or WITHOUT high grade (i.e., grade 3 or sarcomatoid) L
300 Limited to penis - UNKNOWN perineural and/or lymphovascular invasion Confined to penis, NOS Localized, NOS L
400 Corpus spongiosum (including tunica albuginea) - WITHOUT urethral invasion or UNKNOWN if urethral invasion RE
450 Code 400 WITH urethral invasion RE
500 Corpus cavernosum (including tunica albuginea) - WITHOUT urethral invasion OR UNKNOWN if urethral invasion RE
550 Code 500 WITH urethral invasion RE
600 Muscle, NOS - Bulbospongiosus - Ischiocavernosus - Superficial transverse perineal Prostate Pubic bone Scrotum Skin (abdominal, perineum) RE
700 Further contiguous extension - Testis D
800 No evidence of primary tumor U
999 Unknown extension Primary tumor cannot be assessed Not documented in medical record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) Pettaway, C.A., Srigley, J.R., Amin, M.B., et al. **Penis**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017