Summary Stage 2018: Myeloma and Plasma Cell Disorders
Summary Stage 2018
Notes
**Myeloma and Plasma Cell Disorders**
9671 Lymphoplasmacytic lymphoma (except C441, C690, C695-C696)
* C700-C729, C751-C753 (2018-2022 only) (See Note 2)
9731 Plasmacytoma, NOS
9732 Plasma cell myeloma/multiple myeloma
9734 Plasmacytoma, extramedullary (except C441, C690, C695-C696)
9761 Waldenstrom Macroglobulinemia
**Note 1:** The following sources were used in the development of this chapter
* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/)
* Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
* Chapter 82 *Plasma Cell Myeloma and Plasma Cell Disorder*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
**Note 2:** For the histology listed below, this has moved to the Brain, CNS Other, and Intracranial Gland Summary Stage chapters starting with 2023 diagnoses. If you have one of these cases for 2018-2022, then this is the appropriate chapter. If you have one of these cases diagnosed on January 1, 2023 forward, see the appropriate chapter
* 9671
* C700, C710-C719: *Brain*
* C701, C709, C720-C725, C728-C729: *CNS Other*
* C751-C753: *Intracranial Gland*
**Note 3:** Codes 0, 2, and 4 are not applicable for this chapter.
**Note 4:** Plasma cell myeloma/multiple myeloma (9732) is a widely disseminated plasma cell neoplasm, characterized by a single clone of plasma cells derived from B cells that grows in the bone marrow. It is always coded to 7 for systemic involvement.
**Note 5:** Lymphoplasmacytic lymphoma (9671) and Waldenstrom Macroglobulinemia (9761) are now collected with the plasma cell disorders. These are systemic diseases and should always be coded 7.
| SS2018 |
Description |
| 1 |
Localized only
- Single plasmacytoma occurring in bone (osseous or medullary) (9731)
+ WITH or WITHOUT soft tissue extension
- Single plasmacytoma, NOS (9734)
+ Single plasmacytoma occurring outside of bone (extraosseous or extramedullary) (9734) |
| 3 |
Regional lymph node(s) involved only
- Extraosseous plasmacytomas only (9734)
+ Regional lymph node(s), NOS
* Lymph node(s), NOS |
| 7 |
Distant site(s)/lymph node(s) involved
- Lymphoplasmacytic lymphoma (9671)
- Plasma cell myeloma (9732)
+ Multiple myeloma
+ Myeloma, NOS
+ Multiple extraosseous or extramedullary plasmacytomas
+ Multiple osseous or medullary plasmacytomas
+ Multiple plasmacytomas, NOS
- Waldenstrom Macroglobulinemia (9761) |
| 9 |
Unknown if extension or metastasis (applicable for 9731 and 9734 only) |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(5) **Introduction to Hematologic Malignancies**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(6) Bergsagel, P.L., Jaffe, E.S., Leonard, J.P., et al. **Plasma Cell Myeloma and Plasma Cell Disorders**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
