Extranodal Extension Pathological
Notes
**Note 1:** Physician statement of Extranodal Extension (ENE) Pathological or physician pathological staging can be used to code this data item when there is no other information available.
**Note 2:** Extranodal extension is defined as "the extension of a nodal metastasis through the lymph node capsule into adjacent tissue." ENE is the preferred terminology. Other names include: extranodal spread, extracapsular extension, or extracapsular spread."
* "A regional node extending into a distant structure or organ is categorized as ENE and is not recorded as distant metastatic disease."
**Note 3:** Be aware that the rules for coding ENE for head and neck sites compared to non-head and neck sites are different.
**Note 4:** Code the status of extranodal extension assessed on the **surgical resection** specimen for the most involved regional lymph node(s). Do not code ENE for any distant lymph nodes. Code the status of ENE based on the following criteria
* Code 0
* Absence of ENE, positive lymph nodes assessed by lymph node dissection
* 1292: Scope of Regional Lymph Node Surgery must be 3-7
* Code 1
* Presence of ENE assessed by Sentinel Lymph Node biopsy
* Presence of ENE assessed by lymph node dissection
* 1292: Scope of Regional Lymph Node Surgery must be 2-7
* Code 7
* Lymph nodes negative for cancer assessed by Sentinel lymph node biopsy or lymph node dissection
* 1292: Scope of Regional Lymph Node Surgery must be 2-7
* Code 9
* Absence of ENE, positive lymph nodes assessed by Sentinel Lymph Node biopsy
* A positive Sentinel Lymph Node biopsy cannot assess the absence of ENE, only the presence of it. This is because there is not enough surrounding tissue in a Sentinel Lymph node biopsy to accurately assess ENE
* If codes 1 or 7 are used, this indicates that the lymph nodes were surgically resected or a Sentinel Lymph Node biopsy was done and Scope of Regional Lymph Node Surgery [NAACCR Data Item: 1292] must be 2-7
Default
8
Metadata
SSDI
| Code |
Description |
| 0 |
Regional lymph node(s) involved, ENE not present/not identified from surgical resection |
| 1 |
Regional lymph node(s) involved, ENE present/identified from surgical resection |
| 7 |
No lymph node involvement identified from surgical resection (pN0) |
| 8 |
Not applicable: Information not collected for this case
(If this information is required by your standard setter, use of code 8 may result in an edit error) |
| 9 |
Not documented in medical record
No surgical resection of regional lymph node(s)
Non-invasive neoplasm (behavior /2)
Cannot be determined
Pathological assessment of lymph node(s) not done, or unknown if done
Extranodal Extension Pathological not assessed or unknown if assessed |
