Summary Stage 2018: Small Intestine

Summary Stage 2018

Notes

**Small Intestine** 8000-8700, 8720-8790 C170-C173, C178-C179 C170 Duodenum C171 Jejunum C172 Ileum (excluding ileocecal valve C18.0) C173 Meckel diverticulum (site of neoplasm) C178 Overlapping lesion of small intestine C179 Small intestine, NOS **Note 1:** The following sources were used in the development of this chapter * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 18 *Small Intestine*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. * Chapter 30 *Neuroendocrine Tumors of the Duodenum and Ampulla of Vater*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. * Chapter 31 *Neuroendocrine Tumors of the Jejunum and Ileum*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. * *Neuroendocrine Tumors of the Duodenum and Ampulla of Vater,* from the AJCC Cancer Staging System Version 9 (2023). Used with permission of the American College of Surgeons, Chicago, Illinois. * *Neuroendocrine Tumors of the Jejunum and Ileum,* from the AJCC Cancer Staging System Version 9 (2023). Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** See the following chapters for the listed histologies * 8710-8714, 8800-8934, 8940-9138, 9141-9582: *Soft Tissue* * 8935-8936: *GIST* * 9140: *Kaposi Sarcoma* * 9700-9701: *Mycosis Fungoides*

NAACCR Item

NAACCR #764
SS2018 Description
0 In situ, intraepithelial, noninvasive - (Adeno)carcinoma, noninvasive, in a polyp or adenoma
1 Localized only (localized, NOS) - Confined to small intestine, NOS - Extension through wall, NOS - Intraluminal spread to other segments of small intestine or cecum - Invasion of + Intramucosa, NOS + Lamina propria + Mucosa, NOS + Muscularis mucosae + Muscularis, NOS + Muscularis propria + Submucosa (superficial invasion) - Polyp (head, stalk, NOS) - Subserosal tissue/(sub)serosal fat invaded - Transmural, NOS - Wall, NOS
2 Regional by direct extension only - All sites + Abdominal wall (via serosa) + Adjacent organ(s)/structure(s) + Adjacent tissue(s) (connective), NOS + Fat, NOS + Mesenteric fat + Mesentery (adjacent loops of bowel) + Mesothelium + Nonperitonealized perimuscular tissue + Other loops of small intestine + Other segments of small intestine (via serosa) + Retroperitoneum + Serosa + Tunica serosa + Visceral peritoneum - Duodenum (C170) + Ampulla of Vater + Blood vessel(s), major * Aorta * Gastroduodenal artery * Portal vein * Renal vein * Superior mesenteric artery or vein * Vena cava + Diaphragm + Extrahepatic bile duct(s) + Gallbladder + Hepatic flexure + Kidney (right or NOS) + Liver (quadrate lobe, right lobe or NOS) + Omentum + Pancreas (pancreatic duct) + Stomach + Transverse colon + Ureter, right - Jejunum and Ileum (C171, C172) + Colon including appendix
3 Regional lymph node(s) involved only - All sites + Regional lymph node(s), NOS * Lymph node(s), NOS - Duodenum (C170) + Duodenal + Gastroduodenal + Hepatic + Pancreaticoduodenal (inferior) + Pericholodochal (common bile duct) + Pyloric (infrapyloric, subpyloric, NOS) + Retropancreatic + Superior mesenteric - Jejunum and ileum (C171, C172) + Cecal (anterior, posterior, retrocecal) (terminal ileum only) + Ileocecal (ileocolic) (terminal ileum only) + Mesenteric, NOS + Superior mesenteric
4 Regional by BOTH direct extension AND regional lymph node(s) involved - Codes (2) + (3)
7 Distant site(s)/lymph node(s) involved - Distant site(s) (including further contiguous extension) + Jejunum and Ileum (C171, C172) * Bladder * Fallopian tube(s) * Ovary(ies) * Uterus - Distant lymph node(s), NOS + Celiac + Pericholedochal (jejunum and ileum only) - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s)
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) Coit, D.G., Kelsen, D., Hofstetter, W.L., et al. **Small Intestine**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (6) Bergsland, E.K., Woltering, E.A., Klimstra, D.S., et al. **Neuroendocrine Tumors of the Duodenum and Ampulla of Vater**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (7) Woltering, E.A., Bergsland, E.K., et al. **Neuroendocrine Tumors of the Jejunum and Ileum**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (8) **Neuroendocrine Tumors of the Duodenum and Ampulla of Vater,** from the AJCC Cancer Staging System Version 9 (2023). Used with permission of the American College of Surgeons, Chicago, Illinois. (9) **Neuroendocrine Tumors of the Jejunum and Ileum**, from the AJCC Cancer Staging System Version 9 (2023). Used with permission of the American College of Surgeons, Chicago, Illinois.