Summary Stage 2018: Liver
Summary Stage 2018
Notes
**Liver**
8000-8700, 8720-8790
C220
C220 Liver
**Note 1:** The following sources were used in the development of this chapter
* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/)
* Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
* Chapter 22 *Liver*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
**Note 2:** See the following chapters for the listed histologies
* 8710-8714, 8800-8934, 8940-9138, 9141-9582: *Soft Tissue*
* 8935-8936: *GIST*
* 9140: *Kaposi Sarcoma*
* 9700-9701: *Mycosis Fungoides*
**Note 3:** The liver is divided into several lobes as defined below. In the absence of other tumor involvement (lymph node involvement or distant metastasis), code the lobe or segment involvement as follows: If multiple lobes (such as the Caudate lobe and the Left Lobe) are involved, code 2 (Regional). If multiple segments (such as 5 and 6 in the right lobe) in the same lobe are involved, this would be multiple tumors within one lobe, code 1 (Localized).
* Caudate lobe: Segment 1
* Quadrate lobe: Segment 4b
* Left lobe: Segments 2, 3, 4a
* Right lobe: Segments 5, 6, 7, 8
| SS2018 |
Description |
| 0 |
In situ: noninvasive, intraepithelial |
| 1 |
Localized only (localized, NOS)
- Confined to liver, NOS
- Single tumor (one lobe) WITH or WITHOUT vascular invasion
- Multiple (satellite) nodules/tumor confined to one lobe WITH or WITHOUT vascular invasion |
| 2 |
Regional by direct extension only
- Diaphragm
- Extrahepatic bile duct(s)
- Extrahepatic blood vessel(s)
+ Hepatic artery
+ Portal vein
+ Vena cava
- Gallbladder
- Lesser omentum
- Ligament(s)
+ Coronary
+ Falciform
+ Hepatoduodenal
+ Hepatogastric
+ Round (of liver)
+ Triangular
- Peritoneum, NOS
+ Parietal
+ Visceral
- Major vascular invasion, NOS
- More than one lobe involved by contiguous growth (single lesion)
+ WITH or WITHOUT vascular invasion
- Multiple (satellite) nodules/ tumors in more than one lobe of liver or on surface of parenchyma
+ WITH or WITHOUT vascular invasion |
| 3 |
Regional lymph node(s) involved only
- Caval
- Hepatic, NOS
+ Hepatic artery
+ Hepatic pedicle
+ Inferior vena cava
+ Porta hepatis (portal) (hilar) [in hilus of liver]Hepatoduodenal ligament
- Periportal
- Portal vein
- Regional lymph node(s), NOS
+ Lymph node(s), NOS |
| 4 |
Regional by BOTH direct extension AND regional lymph node(s) involved
- Codes (2) + (3) |
| 7 |
Distant site(s)/lymph node(s) involved
- Distant site(s) (including further contiguous extension)
+ Pancreas
+ Pleura
+ Stomach
- Distant lymph node(s), NOS
+ Aortic (para-aortic, periaortic)
+ Cardiac
+ Coronary artery
+ Diaphragmatic, NOS
+ Inferior phrenic nodes
+ Lateral (aortic) (lumbar)
+ Pericardial (pericardiac)
+ Peripancreatic (near head of pancreas only)
+ Posterior mediastinal (tracheoesophageal) including juxtaphrenic nodes
+ Renal artery
+ Retroperitoneal, NOS
- Distant metastasis, NOS
+ Carcinomatosis
+ Distant metastasis WITH or WITHOUT distant lymph node(s) |
| 9 |
Unknown if extension or metastasis |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(5) Abou-Alfa, G.K., Pawlik, T.M., Vauthey, J.N., et al. **Liver**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
