EOD Primary Tumor

This input is used for staging

Notes

**Note 1:** Code 000 (behavior code 2) includes cancer cells confined within the glandular basement membrane (intraepithelial), or described as in situ. **Note 2:** Code 050 (behavior code 3) includes the following: * Intramucosal, NOS * Lamina propria * Mucosa, NOS * Confined to, but not through the muscularis mucosa **Note 3:** Ignore intraluminal extension to adjacent segment(s) of colon/rectum or to the ileum from the cecum; code depth of invasion or extracolonic spread as indicated. **Note 4:** Tumor that is adherent to other organs or structures, macroscopically, is coded as 600 or 700. However, if no tumor is present in the adhesion, microscopically, the classification should be coded to 100-500. **Note 5:** The colon and rectum may be entirely peritonealized, partially peritonealized, or non-peritonealized. Use this list to help distinguish between EOD Primary Tumor codes 300 and 400 (See Note 6). * Entirely peritonealized segments: Cecum, Transverse colon, Sigmoid colon, Rectosigmoid colon * Segmental surfaces that are peritonealized: Anterior and lateral surfaces of: Ascending colon, Descending colon, Hepatic flexure, Splenic flexure, Upper third of rectum. Anterior surface: Middle third of rectum. * Entirely non-peritonealized segment: Lower third of rectum * Segmental surfaces that are non-peritonealized: Posterior surface of: Ascending colon, Descending colon, Hepatic flexure, Splenic flexure, Upper two-thirds of rectum **Note 6:** Invasion into “pericolonic/pericolorectal tissue” can be either code 300 or 400, depending on the primary site and whether it is peritonealized (fully or partially) or not. When extension is described as “pericolonic/pericolorectal tissue” * Code 300 may NOT be used for entirely peritonealized sites (cecum, transverse colon, sigmoid colon, rectosigmoid colon), as this would be equivalent to peritonealized pericolic/perirectal tissue invasion (code 400) * Code 300 may ONLY be used for peritonealized sites (See Note 5) when the extension is described using other terms listed under code 300 (ex. subserosal fat). If there are no other terms used to describe the extension, other than invasion of “pericolorectal tissue”, then assign code 400 * For partially peritonealized sites (See Note 5), “pericolonic/pericolorectal tissue” may indicate invasion of either non-peritonealized (code 300) or peritonealized tissue (code 400) * Check for mention of serosa/peritoneum in the operative report and/or pathology report final diagnosis or gross description to determine the correct code. Again, if other descriptions besides “pericolonic/pericolorectal tissue” are used, assign code 300 or 400 based on the terminology used * If the pathologist does not further describe the “pericolic/perirectal tissues” as either “non-peritonealized pericolic/perirectal tissues” vs “peritonealized pericolic/perirectal tissues” and the operative report and/or gross description does not describe the tumor relation to the serosa/peritoneal surface, and it cannot be determined whether the tumor arises in a peritonealized portion of the colon, code 300. **Note 7:** Tumors characterized by involvement of the serosal surface (visceral peritoneum) by direct extension or perforation in which the tumor cells are continuous with the serosal surface through inflammation are coded to 500.

Default

999

NAACCR Item

NAACCR #772
Code Description SS2018 T
000 In situ: Noninvasive; intraepithelial (Adeno)carcinoma in a polyp or adenoma, noninvasive IS
050 Intramucosal, NOS Lamina propria Mucosa, NOS Confined to, but not through muscularis mucosa L
100 Submucosa (superficial invasion) - Rectum (C209): WITH or WITHOUT intraluminal extension to colon and/or anal canal/anus Through the muscularis mucosa but not into the muscularis propria Confined to polyp (head, stalk, NOS) Confined to colon, rectum, rectosigmoid, NOS Localized, NOS L
200 Muscularis propria invaded - Rectum (C209): WITH or WITHOUT intraluminal extension to colon and/or anal canal/anus L
300 All Sites - Extension through wall, NOS - Invasion through muscularis propria or muscularis, NOS - Rectum (C209): WITH or WITHOUT intraluminal extension to colon and/or anal canal/anus - Perimuscular tissue invaded - Subserosal tissue/(sub)serosal fat invaded - Transmural, NOS - Wall, NOS For non-peritonealized sites (See Notes 5 and 6) or UNKNOWN if peritonealized (for peritonealized sites, see code 400) - Pericolic fat/tissues - Perirectal fat/tissues L
400 All Sites - Adjacent (connective) tissue(s), NOS - Fat, NOS - Gastrocolic ligament (transverse colon and flexures) - Greater omentum (transverse colon and flexures) - Mesentery (including mesenteric fat, mesocolon) - Rectovaginal septum (rectum) - Retroperitoneal fat (ascending and descending colon only) For peritonealized sites (See Notes 5 and 6) (for non-peritonealized sites or UNKNOWN if peritonealized, see code 300) - Pericolic fat/tissues - Perirectal fat/tissues RE
500 Mesothelium Serosa Tunica serosa Invasion of/through the visceral peritoneum RE
600 Adherent to other organs or structures clinically with no microscopic examination Tumor found in adhesion(s) if microscopic examination performed All Colon subsites (C180, C182-C189) - Abdominal wall - Retroperitoneum (excluding fat) - Small intestine Cecum (C180) - Greater omentum Ascending colon (C182) - Greater omentum - Kidney, right - Liver, right lobe - Ureter, right Transverse colon and flexures (C183, C184, C185) - Bile ducts - Gallbladder - Kidney - Liver - Pancreas - Spleen - Stomach Descending colon (C186) - Greater omentum - Kidney, left - Pelvic wall - Spleen - Ureter, left Sigmoid colon (C187) - Greater omentum - Pelvic wall Rectosigmoid (C199) - Cul de sac (rectouterine pouch) - Pelvic wall/pelvic plexuses - Small intestine Rectum (C209) - Anus/anal canal - Bladder (males only) - Cul de sac (rectouterine pouch) - Ductus deferens - Pelvic wall - Prostate - Rectovesical fascia (males only) - Seminal vesicle(s) - Skeletal muscles of pelvic floor - Vagina RE
700 All Colon subsites (C180, C182-C189) - Adrenal (suprarenal) gland - Bladder - Diaphragm - Fallopian tube - Fistula to skin - Gallbladder (except Transverse Colon and Flexures, see code 600) - Other segment(s) of colon via serosa - Ovary(ies) - Uterus Cecum (C180) - Kidney - Liver - Ureter Transverse colon and flexures (C183, C184, C185) - Ureter Sigmoid colon (C187) - Cul de sac (rectouterine pouch) - Ureter Rectosigmoid (C199) - Bladder - Colon via serosa - Fallopian tube(s) - Ovary(ies) - Prostate - Skeletal muscles of pelvic floor - Ureter(s) - Vagina Rectum (C209) - Bladder (females only) - Bone(s) of pelvis - Cervix - Perineum, perianal skin - Sacrum - Sacral plexus - Urethra Further contiguous extension D
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in medical record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) Jessup, J.M., Goldberg, R.M., et al. **Colon and Rectum**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017