EOD Primary Tumor

This input is used for staging


**Note 1:** Code 000 (behavior code 2) includes cancer cells confined within the glandular basement membrane (intraepithelial) or described as in situ or high-grade appendiceal mucinous neoplasms (HAMN) **Note 2:** Code 050 (behavior code 2) for low-grade appendiceal mucinous neoplasms (LAMN) that are confined by the muscularis propria **Note 3:** Code 070 (behavior code 3) includes the following: * Intramucosal, NOS * Lamina propria * Mucosa, NOS * Confined to, but not through the muscularis mucosa **Note 4:** Ignore intraluminal extension to adjacent segment(s) of colon/rectum or to the ileum from the cecum; code depth of invasion or extracolonic spread as indicated. **Note 5:** Mucinous tumors are identified by morphology codes 8480, 8481, and 8490. **Note 6:** Use code 700 for macroscopic adhesions if no pathological confirmation, and for microscopic confirmed tumor in adhesions. However, if no tumor is present in adhesion(s) upon microscopic examination, the classification is based upon extent of tumor invasion into or through the wall (see codes 100-600. **Note 7:** Codes 700 and 750 are used for contiguous extension from the site of origin. Except for intraperitoneal metastases limited to the right lower quadrant (RLQ) of the abdomen for mucinous tumors (see code 600), discontinuous involvement is coded in EOD Mets.




Code Description SS2018 T
000 In situ, intraepithelial, noninvasive (Adeno) carcinoma, noninvasive, in a polyp or adenoma High-grade appendiceal mucinous neoplasm confined by the muscularis propria (HAMN) IS
050 Low-grade appendiceal mucinous neoplasm confined by the muscularis propria (LAMN) Acellular mucin or mucinous epithelium may invade into muscularis propria IS
070 Lamina propria Mucosa (intramucosal, NOS) Muscularis mucosae L
100 Submucosa Confined to appendix, NOS Confined to polyp, NOS Localized, NOS L
200 Muscularis propria L
300 Extension through wall, NOS Invasion through muscularis propria Non-peritonealized pericolic tissues invaded Perimuscular tissue invaded Subserosa Transmural, NOS Wall, NOS L
400 Adjacent tissue(s), NOS Connective tissue Fat, NOS Mesenteric fat Mesentery Mesoappendix Pericolic fat RE
500 Invasion of/through serosa (mesothelium) (visceral peritoneum) RE
600 For mucinous tumors only (ICD-O-3 codes 8480/3, 8481/3, and 8490/3 only) - Peritoneal involvement confined within right lower quadrant + WITHOUT further local extension D
700 Abdominal wall Adherent to other organs or structures Greater omentum Retroperitoneum (excluding fat) Small intestine Tumor found in adhesion(s) if microscopic examination performed RE
750 Mucinous tumors only (ICD-O-3 codes 8480/3, 8481/3, and 8490/3 only) - Structures in code 700 with peritoneal involvement confined within right lower quadrant All tumors - Adrenal (suprarenal) gland - Bladder - Diaphragm - Fallopian tube - Fistula to skin - Gallbladder - Kidney - Liver - Other segment(s) of colon/rectum via serosa - Ovary - Ureter - Uterus Further contiguous extension D
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in medical record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) **Appendix**, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois.