Summary Stage 2018: Appendix
Summary Stage 2018
Notes
**Appendix**
8000-8700, 8720-8790
C181
C181 Appendix
**Note 1:** The following sources were used in the development of this chapter
* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/)
* Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
* Chapter 19 *Appendix - Carcinoma*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
* Chapter 32 *Neuroendocrine Tumors of the Appendix*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
* *Appendix*, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois.
* *Neuroendocrine Tumors of the Appendix*, from the AJCC Cancer Staging System Version 9 (2023). Used with permission of the American College of Surgeons, Chicago, Illinois.
**Note 2:** See the following chapters for the listed histologies
* 8710-8714, 8800-8934, 8940-9138, 9141-9582: *Soft Tissue*
* 8935-8936: *GIST*
* 9140: *Kaposi Sarcoma*
* 9700-9701: *Mycosis Fungoides*
| SS2018 |
Description |
| 0 |
In situ, intraepithelial, noninvasive
- Acellular mucin or mucinous epithelium may invade into the muscularis propria
- (Adeno) carcinoma, noninvasive, in a polyp or adenoma
- Low-grade appendiceal mucinous neoplasm confined by the muscularis propria (LAMN)
- High-grade appendiceal mucinous neoplasm confined by the muscularis propria (HAMN) |
| 1 |
Localized only (localized, NOS)
- Confined to appendix, NOS
- Confined to polyp, NOS
- Extension through wall, NOS
- Invasion through muscularis propria
- Lamina propria
- Mucosa (intramucosal, NOS)
- Muscularis mucosae
- Non-peritonealized pericolic tissues invaded
- Perimuscular tissue invaded
- Submucosa
- Subserosa
- Transmural, NOS
- Wall, NOS |
| 2 |
Regional by direct extension only
- Abdominal wall
- Adherent to other organs or structures
- Adjacent tissue(s), NOS
- Connective tissue
- Fat, NOS
- Greater omentum
- Mesenteric fat
- Mesentery
- Mesoappendix
- Pericolic fat
- Retroperitoneum
- Serosa (mesothelium) (visceral peritoneum)
- Small intestine
- Tumor found in adhesion(s) if microscopic examination performed |
| 3 |
Regional lymph node(s) involved only
- Tumor deposits (TD) in subserosa or mesentery WITHOUT regional lymph node metastases
- Cecal
+ Anterior (prececal)
+ Posterior (retrocecal)
+ Right colic
- Colic, NOS
- Epicolic (adjacent to bowel wall)
- Ileocolic
- Mesenteric, NOS
- Mesocolic, NOS
- Paracolic/pericolic
- Regional lymph node(s), NOS
+ Lymph node(s), NOS |
| 4 |
Regional by BOTH direct extension AND regional lymph node(s) involved
- Codes (2) + (3) |
| 7 |
Distant site(s)/lymph node(s) involved
- Distant site(s) (including further contiguous extension)
+ Adrenal (suprarenal) gland
+ Bladder
+ Diaphragm
+ Fallopian tube
+ Fistula to skin
+ Gallbladder
+ Intraperitoneal spread/peritoneal metastasis
+ Kidney
+ Liver
+ Other segment(s) of colon/rectum via serosa
+ Ovary
+ Ureter
+ Uterus
- Distant lymph node(s), NOS
+ Inferior mesenteric
+ Superior mesenteric
- Distant metastasis, NOS
+ Carcinomatosis
+ Distant metastasis WITH or WITHOUT distant lymph node(s) |
| 9 |
Unknown if extension or metastasis |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(5) Overman, M.J., Jessup, J.M., et al. **Appendix - Carcinoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(6) Woltering, E.A., Bergsland, E.K., et al. **Neuroendocrine Tumors of the Appendix**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(7) **Appendix**, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois.
(8) **Neuroendocrine Tumors of the Appendix**, from the AJCC Cancer Staging System Version 9 (2023). Used with permission of the American College of Surgeons, Chicago, Illinois.
