Hematopoietic, Reticuloendothelial, Immunoproliferative, and Myeloproliferative Neoplasms

Primary Site Histology
C000-C809 9740-9809, 9840-9992
C420, C421, C424 9811-9818, 9823, 9827, 9837
C000-C440, C442-C689, C691-C694, C698-C809 9733, 9820, 9826, 9831-9836

Notes

* M-See list of specific histologies below. All primary sites (C00.0-C80.9) are included unless otherwise specified. * Schema includes only preferred terms from ICD-O-3. * Plasmacytomas (9731 and 9734) and Multiple Myeloma (9732), except for cases with primary site C441, C690 and C695-C696, have been moved to the MyelomaPlasmaCellDisorder schema in V0203. 9733 - Plasma cell leukemia [except C441, C690, C695-C696] 9740 - Mast cell sarcoma 9741 - Malignant mastocytosis 9742 - Mast cell leukemia 9750 - Malignant histiocytosis 9752 - Langerhans cell histiocytosis, unifocal\* (see new reportable code 9751/3) 9753 - Langerhans cell histiocytosis, multifocal\* (see new reportable code 9751/3) 9754 - Langerhans cell histiocytosis disseminated 9755 - Histiocytic sarcoma 9756 - Langerhans cell sarcoma 9757 - Interdigitating dendritic cell sarcoma 9758 - Follicular dendritic cell sarcoma 9760 - Immunoproliferative disease, NOS 9761 - Waldenstrom macroglobulinemia 9762 - Heavy chain disease, NOS 9764 - Immunoproliferative small intestinal disease 9765 - Monoclonal gammopathy of undetermined significance\* 9766 - Angiocentric immunoproliferative lesion\* 9767 - Angioimmunoblastic lymphadenopathy\* 9768 - T-gamma lymphoproliferative disease\* 9769 - Immunoglobulin deposition disease\* 9800 - Leukemia, NOS 9801 - Acute leukemia, NOS 9805 - Acute biphenotypic leukemia 9820 - Lymphoid leukemia, NOS [except C441, C690, C695-C696] 9823 - B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma [C420, C421, or C424 ONLY] 9826 - Burkitt cell leukemia leukemia [except C441, C690, C695-C696] 9827 - Adult T-cell leukemia/lymphoma (HTLV-1 positive)[C420, C421, or C424 ONLY] 9832 - Prolymphocytic leukemia, NOS [except C441, C690, C695-C696] 9833 - Prolymphocytic leukemia, B-cell type [except C441, C690, C695-C696] 9834 - Prolymphocytic leukemia, T-cell type [except C441, C690, C695-C696] 9835 - Precursor cell lymphoblastic leukemia, NOS [except C441, C690, C695-C696] 9836 - Precursor B-cell lymphoblastic leukemia [except C441, C690, C695-C696] 9837 - Precursor T-cell lymphoblastic leukemia [see 9837 below, new definition] 9840 - Acute myeloid leukemia, M6 type 9860 - Myeloid leukemia, NOS 9861 - Acute myeloid leukemia, NOS 9863 - Chronic myeloid leukemia 9866 - Acute promyelocytic leukemia 9867 - Acute myelomonocytic leukemia 9870 - Acute basophilic leukemia 9871 - Acute myeloid leukemia with abnormal marrow, eosinophils 9872 - Acute myeloid leukemia, minimal differentiation 9873 - Acute myeloid leukemia without maturation 9874 - Acute myeloid leukemia with maturation 9875 - Chronic myelogenous leukemia, BCR/ABL positive 9876 - Atypical chronic myeloid leukemia BCR/ABL negative 9891 - Acute monocytic leukemia 9895 - Acute myeloid leukemia with multilineage dysplasia 9896 - Acute myeloid leukemia, t(8;21)(q22;q22) 9897 - Acute myeloid leukemia, 11q23 abnormalities 9910 - Acute megakaryoblastic leukemia 9920 - Therapy-related acute myeloid leukemia, NOS 9930 - Myeloid sarcoma 9931 - Acute panmyelosis with myelofibrosis 9940 - Hairy cell leukemia 9945 - Chronic myelomonocytic leukemia, NOS 9946 - Juvenile myelomonocytic leukemia 9948 - Aggressive NK-cell leukemia 9950 - Polycythemia (rubra) vera 9960 - Chronic myeloproliferative disease, NOS 9961 - Myelosclerosis with myeloid metaplasia 9962 - Essential thrombocythemia 9963 - Chronic neutrophilic leukemia 9964 - Hypereosinophilic syndrome 9970 - Lymphoproliferative disorder, NOS\* 9975 - Myeloproliferative disease, NOS\* 9980 - Refractory anemia, NOS 9982 - Refractory anemia with sideroblasts 9983 - Refractory anemia with excess blasts 9984 - Refractory anemia with excess blasts in transformation 9985 - Refractory cytopenia with multilineage dysplasia 9986 - Myelodysplastic syndrome with 5q deletion (5q-) syndrome 9987 - Therapy-related myelodysplastic syndrome, NOS 9989 - Myelodysplastic syndrome, NOS * The following ICD-O codes were added to the reportable list for Hematopoietic diseases. These are from the "WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, 3rd edition" publication, which was released in 2008. These new codes have been incorporated into the new Hematopoietic and Lymphoid Neoplasm MP/H rules. Use these only for cases diagnosed on January 1, 2010 and forward. 9751 - Langerhans cell histiocytosis, NOS 9806 - Mixed phenotype acute leukemia with t(9;22(q34;q11.2); BCR-ABL1 9807 - Mixed phenotype acute leukemia with t(v;11q23); MLL, rearranged 9808 - Mixed phenotype acute leukemia, B/myeloid, NOS 9809 - Mixed phenotype acute leukemia, T/myeloid, NOS 9811 - B lymphoblastic leukemia/lymphoma, NOS [C420, C421, or C424 ONLY] 9812 - B lymphoblastic leukemia/lymphoma with t(9;22))q34;q11.2); BCR-ABL1 [C420, C421, or C424 ONLY] 9813 - B lymphoblastic leukemia/lymphoma with t(v;11q23); MLL rearranged [C420, C421, or C424 ONLY] 9814 - B lymphoblastic leukemia/lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) [C420, C421, or C424 ONLY] 9815 - B lymphoblastic/lymphoma with hyperdiploidy[C420, C421, or C424 ONLY] 9816 - B lymphoblastic/lymphoma with hypodiploidy (hypodiploid ALL) [C420, C421, or C424 ONLY] 9817 - B lymphoblastic/lymphoma with t(5;14)(q31;q32); IL3-IGH [C420, C421, or C424 ONLY] 9818 - B lymphoblastic/lymphoma with t(1;19)(q23;p13.3); E2A PBX1 (TCF3 PBX1) [C420, C421, or C424 ONLY] 9831 - T-cell large granular lymphocytic leukemia [except C441, C690, C695-C696] 9837 - T lymphoblastic leukemia/lymphoma [C420, C421, or C424 ONLY] 9865 - Acute myeloid leukemia with t(6;9)([23;q34) DEK-NUP214 9869 - Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26;2); RPN1EVI1 9898 - Myeloid leukemia associated with Down Syndrome 9911 - Acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 9965 - Myeloid and lymphoid neoplasms with PDGFRA rearrangement 9966 - Myeloid neoplasm with PDGFRB rearrangement 9967 - Myeloid and lymphoid neoplasm with FGFR1 abnormalities 9971 - Polymorphic PTLD 9975 - Myeloproliferative neoplasm, unclassifiable 9991 - Refractory neutropenia 9992 - Refractory thrombocytopenia \*Usually considered of uncertain/borderline behavior **Note**: AJCC does not define TNM staging for this site.

Data Items

Name Default Value Used for Staging NAACCR Item Metadata
Primary Site <BLANK> Yes NAACCR #400
primarySite 		None
Histology <BLANK> Yes NAACCR #522
histologicTypeIcdO3 		None
Year of Diagnosis <BLANK> Yes NAACCR #390
dateOfDiagnosis 		None
CS Version Input Original <BLANK> Yes NAACCR #2935
csVersionInputOriginal 		None
Behavior ICD-O-3 <BLANK> No NAACCR #523
behaviorCodeIcdO3 		None
Grade <BLANK> No NAACCR #440
grade 		None
Age at Diagnosis <BLANK> No NAACCR #230
ageAtDiagnosis 		None
Lymph-vascular Invasion 8 No NAACCR #1182
lymphVascularInvasion 		None
CS Tumor Size 988 No NAACCR #2800
csTumorSize 		None
CS Extension 999 Yes NAACCR #2810
csExtension 		None
CS Tumor Size/Ext Eval 9 Yes NAACCR #2820
csTumorSizeExtEval 		None
CS Lymph Nodes 988 Yes NAACCR #2830
csLymphNodes 		None
CS Lymph Nodes Eval 9 Yes NAACCR #2840
csLymphNodesEval 		None
Regional Nodes Positive 99 No NAACCR #820
regionalNodesPositive 		None
Regional Nodes Examined 99 No NAACCR #830
regionalNodesExamined 		None
CS Mets at DX 98 Yes NAACCR #2850
csMetsAtDx 		None
CS Mets Eval 9 Yes NAACCR #2860
csMetsEval 		None
SSF1: JAK2 (also known as Janus Kinase 2 and JAK2 Exon 12) 999 No NAACCR #2880
csSiteSpecificFactor1 		CCCR_IVA_COLLECT_IF_AVAILABLE_IN_PATH_REPORT
COC_CLINICALLY_SIGNIFICANT
SEER_CLINICALLY_SIGNIFICANT
SSF2: CS Site-Specific Factor 2 988 No NAACCR #2890
csSiteSpecificFactor2 		UNDEFINED_SSF
SSF3: CS Site-Specific Factor 3 988 No NAACCR #2900
csSiteSpecificFactor3 		UNDEFINED_SSF
SSF4: CS Site-Specific Factor 4 988 No NAACCR #2910
csSiteSpecificFactor4 		UNDEFINED_SSF
SSF5: CS Site-Specific Factor 5 988 No NAACCR #2920
csSiteSpecificFactor5 		UNDEFINED_SSF
SSF6: CS Site-Specific Factor 6 988 No NAACCR #2930
csSiteSpecificFactor6 		UNDEFINED_SSF
SSF7: CS Site-Specific Factor 7 988 No NAACCR #2861
csSiteSpecificFactor7 		UNDEFINED_SSF
SSF8: CS Site-Specific Factor 8 988 No NAACCR #2862
csSiteSpecificFactor8 		UNDEFINED_SSF
SSF9: CS Site-Specific Factor 9 988 No NAACCR #2863
csSiteSpecificFactor9 		UNDEFINED_SSF
SSF10: CS Site-Specific Factor 10 988 No NAACCR #2864
csSiteSpecificFactor10 		UNDEFINED_SSF
SSF11: CS Site-Specific Factor 11 988 No NAACCR #2865
csSiteSpecificFactor11 		UNDEFINED_SSF
SSF12: CS Site-Specific Factor 12 988 No NAACCR #2866
csSiteSpecificFactor12 		UNDEFINED_SSF
SSF13: CS Site-Specific Factor 13 988 No NAACCR #2867
csSiteSpecificFactor13 		UNDEFINED_SSF
SSF14: CS Site-Specific Factor 14 988 No NAACCR #2868
csSiteSpecificFactor14 		UNDEFINED_SSF
SSF15: CS Site-Specific Factor 15 988 No NAACCR #2869
csSiteSpecificFactor15 		UNDEFINED_SSF
SSF16: CS Site-Specific Factor 16 988 No NAACCR #2870
csSiteSpecificFactor16 		UNDEFINED_SSF
SSF17: CS Site-Specific Factor 17 988 No NAACCR #2871
csSiteSpecificFactor17 		UNDEFINED_SSF
SSF18: CS Site-Specific Factor 18 988 No NAACCR #2872
csSiteSpecificFactor18 		UNDEFINED_SSF
SSF19: CS Site-Specific Factor 19 988 No NAACCR #2873
csSiteSpecificFactor19 		UNDEFINED_SSF
SSF20: CS Site-Specific Factor 20 988 No NAACCR #2874
csSiteSpecificFactor20 		UNDEFINED_SSF
SSF21: CS Site-Specific Factor 21 988 No NAACCR #2875
csSiteSpecificFactor21 		UNDEFINED_SSF
SSF22: CS Site-Specific Factor 22 988 No NAACCR #2876
csSiteSpecificFactor22 		UNDEFINED_SSF
SSF23: CS Site-Specific Factor 23 988 No NAACCR #2877
csSiteSpecificFactor23 		UNDEFINED_SSF
SSF24: CS Site-Specific Factor 24 988 No NAACCR #2878
csSiteSpecificFactor24 		UNDEFINED_SSF
SSF25: CS Site-Specific Factor 25 988 No NAACCR #2879
csSiteSpecificFactor25 		UNDEFINED_SSF

Initial Context

Staging Methods

Expand All | Collapse All

T

Start

Additional Context
stor_ajcc6_tdescriptor = <BLANK>
stor_ajcc7_tdescriptor = <BLANK>
t2000 = <BLANK>
stor_ajcc6_t = <BLANK>
ajcc6_tdescriptor = ERROR
stor_ajcc7_t = <BLANK>
t77 = <BLANK>
ajcc7_tdescriptor = ERROR
ajcc6_t = <BLANK>
ajcc7_t = <BLANK>

Next Step

  2. Extension
  3. t77
    t2000
    ajcc7_t
    ajcc6_t

Next Step

  2. Extension Eval
  3. ajcc7_tdescriptor

Next Step

  2. AJCC Descriptor Codes
  3. stor_ajcc7_tdescriptor

Next Step

  2. AJCC T Descriptor Code Cleanup
  3. ajcc7_tdescriptor
    stor_ajcc7_tdescriptor

Next Step

  2. AJCC 7 T Codes
  3. stor_ajcc7_t

Next Step

  2. Extension Eval
  3. ajcc6_tdescriptor

Next Step

  2. AJCC Descriptor Codes
  3. stor_ajcc6_tdescriptor

Next Step

  2. AJCC T Descriptor Code Cleanup
  3. ajcc6_tdescriptor
    stor_ajcc6_tdescriptor

Next Step

  2. AJCC 6 T Codes
  3. stor_ajcc6_t

End

N

Start

Additional Context
stor_ajcc6_ndescriptor = <BLANK>
n77 = <BLANK>
ajcc7_n = <BLANK>
stor_ajcc7_ndescriptor = <BLANK>
ajcc6_n = <BLANK>
n2000 = <BLANK>
ajcc6_ndescriptor = ERROR
stor_ajcc6_n = <BLANK>
ajcc7_ndescriptor = ERROR
stor_ajcc7_n = <BLANK>

Next Step

  2. Nodes
  3. ajcc7_n
    ajcc6_n
    n2000
    n77

Next Step

  2. Nodes Eval
  3. ajcc7_ndescriptor

Next Step

  2. AJCC Descriptor Codes
  3. stor_ajcc7_ndescriptor

Next Step

  2. AJCC N Descriptor Code Cleanup
  3. ajcc7_ndescriptor
    stor_ajcc7_ndescriptor

Next Step

  2. AJCC 7 N Codes
  3. stor_ajcc7_n

Next Step

  2. Nodes Eval
  3. ajcc6_ndescriptor

Next Step

  2. AJCC Descriptor Codes
  3. stor_ajcc6_ndescriptor

Next Step

  2. AJCC N Descriptor Code Cleanup
  3. ajcc6_ndescriptor
    stor_ajcc6_ndescriptor

Next Step

  2. AJCC 6 N Codes
  3. stor_ajcc6_n

End

M

Start

Additional Context
stor_ajcc6_m = <BLANK>
m77 = <BLANK>
m2000 = <BLANK>
ajcc6_m = <BLANK>
ajcc7_m = <BLANK>
stor_ajcc7_mdescriptor = <BLANK>
ajcc7_mdescriptor = ERROR
ajcc6_mdescriptor = ERROR
stor_ajcc7_m = <BLANK>
stor_ajcc6_mdescriptor = <BLANK>

Next Step

  2. Mets
  3. ajcc7_m
    ajcc6_m
    m77
    m2000

Next Step

  2. Mets Eval
  3. ajcc7_mdescriptor

Next Step

  2. AJCC Descriptor Codes
  3. stor_ajcc7_mdescriptor

Next Step

  2. AJCC M Descriptor Code Cleanup
  3. ajcc7_mdescriptor
    stor_ajcc7_mdescriptor

Next Step

  2. AJCC 7 M Codes
  3. stor_ajcc7_m

Next Step

  2. Mets Eval
  3. ajcc6_mdescriptor

Next Step

  2. AJCC Descriptor Codes
  3. stor_ajcc6_mdescriptor

Next Step

  2. AJCC M Descriptor Code Cleanup
  3. stor_ajcc6_mdescriptor
    ajcc6_mdescriptor

Next Step

  2. AJCC 6 M Codes
  3. stor_ajcc6_m

End

AJCC 7 Excluded

Start

Additional Context
stor_ajcc7_mdescriptor = N
ajcc7_mdescriptor = <BLANK>
stor_ajcc7_stage = 888
stor_ajcc7_tdescriptor = N
stor_ajcc7_t = 888
stor_ajcc7_ndescriptor = N
ajcc7_t = NA
stor_ajcc7_n = 888
ajcc7_m = NA
ajcc7_n = NA
stor_ajcc7_m = 888
ajcc7_tdescriptor = <BLANK>
ajcc7_ndescriptor = <BLANK>
ajcc7_stage = NA

End

AJCC 6

Start

Additional Context
stor_ajcc6_stage = <BLANK>
ajcc6_stage = <BLANK>

Next Step

  2. AJCC6 Stage
  3. ajcc6_stage

Next Step

  2. AJCC 6 Stage Codes
  3. stor_ajcc6_stage

End

Summary Stage

Start

  1. m77
    n77
    t77
  2. Summary Stage
  3. ss77

Next Step

  2. Summary Stage Codes
  3. stor_ss77

Next Step

  2. Summary Stage
  3. ss2000

Next Step

  2. Summary Stage Codes
  3. stor_ss2000

End

Validate AJCC7 Year

Exclusion Table

Year of Diagnosis CS Version Input Original
2010-{{ctx_year_current}} <Any value>
<BLANK> 020000-999999

Start

Additional Context
ajcc7_n = <BLANK>
stor_ajcc7_ndescriptor = <BLANK>
stor_ajcc7_stage = <BLANK>
ajcc7_m = <BLANK>
ajcc7_mdescriptor = <BLANK>
stor_ajcc7_mdescriptor = <BLANK>
ajcc7_stage = <BLANK>
stor_ajcc7_tdescriptor = <BLANK>
ajcc7_tdescriptor = <BLANK>
stor_ajcc7_t = <BLANK>
ajcc7_ndescriptor = <BLANK>
stor_ajcc7_m = <BLANK>
ajcc7_t = <BLANK>
stor_ajcc7_n = <BLANK>

End

Validate AJCC6 Year

Exclusion Table

Year of Diagnosis CS Version Input Original
2004-{{ctx_year_current}} <Any value>
<BLANK> 020500-999999, 020440, 020302, 020200, 020100, 020001, 010401, 010400, 010300, 010200, 010100, 010005, 010004, 010003, 010002, 010000, 000937

Start

Additional Context
stor_ajcc6_ndescriptor = <BLANK>
n77 = <BLANK>
stor_ajcc6_m = <BLANK>
stor_ajcc7_stage = <BLANK>
ajcc6_m = <BLANK>
stor_ajcc6_stage = <BLANK>
t2000 = <BLANK>
ss77 = <BLANK>
stor_ss77 = <BLANK>
ajcc6_tdescriptor = <BLANK>
n2000 = <BLANK>
stor_ajcc6_t = <BLANK>
t77 = <BLANK>
ajcc6_t = <BLANK>
stor_ajcc6_n = <BLANK>
m77 = <BLANK>
m2000 = <BLANK>
ss2000 = <BLANK>
ajcc6_ndescriptor = <BLANK>
ajcc6_n = <BLANK>
ajcc6_stage = <BLANK>
stor_ajcc6_mdescriptor = <BLANK>
stor_ajcc6_tdescriptor = <BLANK>
ajcc6_mdescriptor = <BLANK>
stor_ss2000 = <BLANK>

End

Outputs

Name Default Value Description NAACCR Item Metadata
Schema Number 151 CS assigned schema number. None None
CS Version Derived 020550 Collaborative Staging (CS) version used to derive the CS output fields. NAACCR #2936
csVersionDerived 		None
AJCC6 T <BLANK> None None
AJCC6 T Descriptor <BLANK> None None
AJCC6 N <BLANK> None None
AJCC6 N Descriptor <BLANK> None None
AJCC6 M <BLANK> None None
AJCC6 M Descriptor <BLANK> None None
AJCC6 Stage Group <BLANK> None None
AJCC7 T <BLANK> None None
AJCC7 T Descriptor <BLANK> None None
AJCC7 N <BLANK> None None
AJCC7 N Descriptor <BLANK> None None
AJCC7 M <BLANK> None None
AJCC7 M Descriptor <BLANK> None None
AJCC7 Stage Group <BLANK> None None
Summary Stage T 1977 <BLANK> None None
Summary Stage N 1977 <BLANK> None None
Summary Stage M 1977 <BLANK> None None
Summary Stage Group 1977 <BLANK> None None
Summary Stage T 2000 <BLANK> None None
Summary Stage N 2000 <BLANK> None None
Summary Stage M 2000 <BLANK> None None
Summary Stage Group 2000 <BLANK> None None
AJCC6 T (Storage) <BLANK> NAACCR #2940
derivedAjcc6T 		None
AJCC6 T Descriptor (Storage) <BLANK> NAACCR #2950
derivedAjcc6TDescript 		None
AJCC6 N (Storage) <BLANK> NAACCR #2960
derivedAjcc6N 		None
AJCC6 N Descriptor (Storage) <BLANK> NAACCR #2970
derivedAjcc6NDescript 		None
AJCC6 M (Storage) <BLANK> NAACCR #2980
derivedAjcc6M 		None
AJCC6 M Descriptor (Storage) <BLANK> NAACCR #2990
derivedAjcc6MDescript 		None
AJCC6 Stage Group (Storage) <BLANK> NAACCR #3000
derivedAjcc6StageGrp 		None
AJCC7 T (Storage) <BLANK> NAACCR #3400
derivedAjcc7T 		None
AJCC7 T Descriptor (Storage) <BLANK> NAACCR #3402
derivedAjcc7TDescript 		None
AJCC7 N (Storage) <BLANK> NAACCR #3410
derivedAjcc7N 		None
AJCC7 N Descriptor (Storage) <BLANK> NAACCR #3412
derivedAjcc7NDescript 		None
AJCC7 M (Storage) <BLANK> NAACCR #3420
derivedAjcc7M 		None
AJCC7 M Descriptor (Storage) <BLANK> NAACCR #3422
derivedAjcc7MDescript 		None
AJCC7 Stage Group (Storage) <BLANK> NAACCR #3430
derivedAjcc7StageGrp 		None
Summary Stage Group 1977 (Storage) <BLANK> NAACCR #3010
derivedSs1977 		None
Summary Stage Group 2000 (Storage) <BLANK> NAACCR #3020
derivedSs2000 		None