Hematopoietic, Reticuloendothelial, Immunoproliferative, and Myeloproliferative Neoplasms

Primary Site Histology Staging Type
C000-C809 9740-9809, 9840-9992 Summary Stage only
C420, C421, C424 9811-9818, 9823, 9827, 9837 Summary Stage only
C000-C440, C442-C689, C691-C694, C698-C809 9820, 9826, 9831-9834 Summary Stage only

If you are working with a site/histology that only summary stages and you need to directly code it, please use the SEER Summary Stage 2000 manual


**Note 1:** TNM is not defined for this schema. If directly assigning Summary Stage 2000 (SS2000), use the *Hematopoietic, Reticuloendothelial, Immunoproliferative, and Myeloproliferative Neoplasms* chapter on page 286 of the [SS2000 on-line manual](https://seer.cancer.gov/tools/ssm/ssm2000/SSSM2000-122012.pdf#page=286). **Note 2:** M-See list of specific histologies below, effective for cases diagnosed 2010 and forward. All primary sites (C000-C809) are included unless otherwise specified. **Note 3:** Schema includes the preferred terms based on the *2008 WHO Classification of Haematopoietic and Lymphoid Tissues* 9740 Mast cell sarcoma 9741 Malignant mastocytosis 9742 Mast cell leukemia 9751 Langerhans cell histiocytosis, NOS 9755 Histiocytic sarcoma 9756 Langerhans cell sarcoma 9757 Interdigitating dendritic cell sarcoma 9758 Follicular dendritic cell sarcoma 9761 Waldenstrom macroglobulinemia 9762 Heavy chain disease, NOS 9800 Leukemia, NOS 9801 Acute leukemia, NOS 9806 Mixed phenotype acute leukemia with t(9;22(q34;q11.2); BCR-ABL1 9807 Mixed phenotype acute leukemia with t(v;11q23); MLL, rearranged 9808 Mixed phenotype acute leukemia, B/myeloid, NOS 9809 Mixed phenotype acute leukemia, T/myeloid, NOS 9811 B lymphoblastic leukemia/lymphoma, NOS [C421 ONLY] 9812 B lymphoblastic leukemia/lymphoma with t(9;22))q34;q11.2); BCR-ABL1 [C421 ONLY] 9813 B lymphoblastic leukemia/lymphoma with t(v;11q23); MLL rearranged [C421 ONLY] 9814 B lymphoblastic leukemia/lymphoma with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) [C421 ONLY] 9815 B lymphoblastic/lymphoma with hyperdiploidy [C421 ONLY] 9816 B lymphoblastic/lymphoma with hypodiploidy (hypodiploid ALL) [C421 ONLY] 9817 B lymphoblastic/lymphoma with t(5;14)(q31;q32); IL3-IGH [C421 ONLY] 9818 B lymphoblastic/lymphoma with t(1;19)(q23;p13.3); E2A PBX1 (TCF3 PBX1) [C421 ONLY] 9820 Lymphoid leukemia, NOS 9823 B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma [C421 ONLY] 9826 Burkitt cell leukemia leukemia 9827 Adult T-cell leukemia/lymphoma (HTLV-1 positive)[C421 ONLY] 9831 T-cell large granular lymphocytic leukemia 9832 Prolymphocytic leukemia, NOS 9833 Prolymphocytic leukemia, B-cell type 9834 Prolymphocytic leukemia, T-cell type 9837 T lymphoblastic leukemia/lymphoma [C421 ONLY] 9840 Acute myeloid leukemia, M6 type 9860 Myeloid leukemia, NOS 9861 Acute myeloid leukemia, NOS 9863 Chronic myeloid leukemia 9865 Acute myeloid leukemia with t(6;9)([23;q34) DEK-NUP214 9866 Acute promyelocytic leukemia 9867 Acute myelomonocytic leukemia 9869 Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26;2); RPN1EVI1 9870 Acute basophilic leukemia 9871 Acute myeloid leukemia with abnormal marrow, eosinophils 9872 Acute myeloid leukemia, minimal differentiation 9873 Acute myeloid leukemia without maturation 9874 Acute myeloid leukemia with maturation 9875 Chronic myelogenous leukemia, BCR/ABL positive 9876 Atypical chronic myeloid leukemia BCR/ABL negative 9891 Acute monocytic leukemia 9895 Acute myeloid leukemia with multilineage dysplasia 9896 Acute myeloid leukemia, t(8;21)(q22;q22) 9897 Acute myeloid leukemia, 11q23 abnormalities 9898 Myeloid leukemia associated with Down Syndrome 9910 Acute megakaryoblastic leukemia 9911 Acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 9920 Therapy-related acute myeloid leukemia, NOS 9930 Myeloid sarcoma 9931 Acute panmyelosis with myelofibrosis 9940 Hairy cell leukemia 9945 Chronic myelomonocytic leukemia, NOS 9946 Juvenile myelomonocytic leukemia 9948 Aggressive NK-cell leukemia 9950 Polycythemia (rubra) vera 9961 Myelosclerosis with myeloid metaplasia 9962 Essential thrombocythemia 9963 Chronic neutrophilic leukemia 9964 Hypereosinophilic syndrome 9965 Myeloid and lymphoid neoplasms with PDGFRA rearrangement 9966 Myeloid neoplasm with PDGFRB rearrangement 9967 Myeloid and lymphoid neoplasm with FGFR1 abnormalities 9971 Polymorphic PTLD 9975 Myeloproliferative neoplasm, unclassifiable 9980 Refractory anemia, NOS 9982 Refractory anemia with sideroblasts 9983 Refractory anemia with excess blasts 9985 Refractory cytopenia with multilineage dysplasia 9986 Myelodysplastic syndrome with 5q deletion (5q-) syndrome 9989 Myelodysplastic syndrome, NOS 9991 Refractory neutropenia 9992 Refractory thrombocytopenia

Main Data Items

Name Default Value Used for Staging NAACCR Item Required By Metadata
SSF1: JAK2 (also known as Janus Kinase 2 and JAK2 Exon 12) 999 No NAACCR #2880

Additional Data Items

Name Default Value Used for Staging NAACCR Item Required By Metadata
Year of Diagnosis <BLANK> No NAACCR #390
Primary Site <BLANK> Yes NAACCR #400
Histology <BLANK> Yes NAACCR #522

Initial Context

Staging Methods

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Name Default Value Description NAACCR Item Metadata
Derived Version {{ctx_alg_version}} None None
Derived SEER Clin Stage Group 88 NAACCR #3610
Derived SEER Path Stage Group 88 NAACCR #3605
Derived SEER Combined Stage Group 88 NAACCR #3614
Derived SEER Combined T 88 NAACCR #3616
Derived SEER Combined N 88 NAACCR #3618
Derived SEER Combined M 88 NAACCR #3620
Derived SEER Combined T Source <BLANK> NAACCR #3622
Derived SEER Combined N Source <BLANK> NAACCR #3624
Derived SEER Combined M Source <BLANK> NAACCR #3626