Colon (excluding Appendix, Gastrointestinal Stromal Tumor, and Neuroendocrine Tumor)

Primary Site Histology Staging Type
C180, C182-C189 8000-8152, 8154-8231, 8243-8245, 8247-8248, 8250-8576, 8940-8950, 8980-8981 TNM 7 and Summary Stage
C180, C182-C189 8577-8934, 8951-8979, 8982-9136, 9141-9582, 9700-9701 Summary Stage only

If you are working with a site/histology that only summary stages and you need to directly code it, please use the SEER Summary Stage 2000 manual

Notes

C180 Cecum C182 Ascending colon C183 Hepatic flexure of colon C184 Transverse colon C185 Splenic flexure of colon C186 Descending colon C187 Sigmoid colon C188 Overlapping lesion of colon C189 Colon, NOS **Note 1:** This schema is based on the UICC chapter *Colon and Rectum,* pages 100-105. * Primary sites C188 and C189 are listed in the chapter heading but are not specified in the anatomic subsites in this chapter of the UICC manual; however, they are included in this schema and TNM staged if appropriate histology criteria are met **Note 2:** In addition to directly assigning TNM, Summary Stage 2000 (SS2000) must be captured. If directly assigning SS2000, use the *Colon* chapter on page 94 of the [SS2000 on-line manual](https://seer.cancer.gov/tools/ssm/ssm2000/SSSM2000-122012.pdf#page=94).

Main Data Items

Name Default Value Used for Staging NAACCR Item Required By Metadata
Clinical T <BLANK> Yes NAACCR #940 None
Clinical N <BLANK> Yes NAACCR #950 None
Clinical M <BLANK> Yes NAACCR #960 None
TNM Clin Stage Group 99 Yes NAACCR #970 None
Pathologic T <BLANK> Yes NAACCR #880 None
Pathologic N <BLANK> Yes NAACCR #890 None
Pathologic M <BLANK> Yes NAACCR #900 None
TNM Path Stage Group 99 Yes NAACCR #910 None
SSF1: Carcinoembryonic Antigen (CEA) 999 No NAACCR #2880 CCCR/Canada
COC
SEER
None
SSF3: Carcinoembryonic Antigen (CEA) Lab Value 988 No NAACCR #2900 CCCR/Canada
COC
None
SSF4: Tumor Deposits 999 No NAACCR #2910 CCCR/Canada
COC
SEER
None
SSF5: Tumor Regression Grade 988 No NAACCR #2920 None None
SSF6: Circumferential Resection Margin (CRM) 999 No NAACCR #2930 CCCR/Canada
COC
SEER
None
SSF7: Microsatellite Instability (MSI) 988 No NAACCR #2861 None None
SSF8: Perineural Invasion 999 No NAACCR #2862 CCCR/Canada
COC
SEER
None
SSF9: KRAS 999 No NAACCR #2863 CCCR/Canada
COC
SEER
None
SSF10: 18q Loss of Heterozygosity (LOH) 988 No NAACCR #2864 None None

Additional Data Items

Name Default Value Used for Staging NAACCR Item Required By Metadata
Year of Diagnosis <BLANK> No NAACCR #390 None
Primary Site <BLANK> Yes NAACCR #400 None
Histology <BLANK> Yes NAACCR #522 None
RX Summ Systemic/Surgery Sequence <BLANK> Yes NAACCR #1639 None
RX Summ Surgery/Radiation Sequence <BLANK> Yes NAACCR #1380 None
Regional Nodes Positive <BLANK> Yes NAACCR #820 None

Initial Context

Staging Methods

Expand All | Collapse All

TNM 7 Stage

Inclusion Table

Histology
8000-8152
8154-8231
8243-8245
8247
8248
8250-8576
8940-8950
8980-8981

Start

Additional Context
Pathologic Stage Group = 90
Clinical Stage Group = 90

Next Step

  1. Parse T
  2. clin_t_prefix
    tmp_clin_t

Next Step

  1. Parse N
  2. clin_n_prefix
    tmp_clin_n

Next Step

  1. Parse M
  2. tmp_clin_m
    clin_m_prefix

Next Step

  1. Parse T
  2. tmp_path_t
    path_t_prefix

Next Step

  1. Parse N
  2. tmp_path_n
    path_n_prefix

Next Step

  1. Parse M
  2. tmp_path_m
    path_m_prefix

Next Step

  1. Determine Default T
  2. Source T
    tmp_path_t
    tmp_clin_t
    tmp_combined_t

Next Step

  1. Determine Default N
  2. tmp_combined_n
    tmp_clin_n
    tmp_path_n
    Source N

Next Step

  1. Determine Default M
  2. tmp_path_m
    tmp_combined_m
    tmp_clin_m
    Source M

Next Step

  1. TNM 7 Stage Group
  2. Clinical Stage Group

Next Step

  1. TNM 7 Path Stage Group
  2. Pathologic Stage Group

Next Step

  1. Adjustments for No Clin or No Path
  2. tmp_combined_n
    tmp_combined_m
    Source T
    Clinical Stage Group
    Pathologic Stage Group
    Source N
    tmp_combined_t
    Source M

End

Combined Stage

Inclusion Table

Histology
8000-8152
8154-8231
8243-8245
8247
8248
8250-8576
8940-8950
8980-8981

Start

Additional Context
Combined Stage Group = 90
Combined N = 90
Combined M = 90
Combined T = 90

Next Step

  1. Stop if No Clin and No Path
  2. Combined M
    Combined N
    Source T
    tmp_continue
    Combined T
    Combined Stage Group
    Source N
    Source M

Next Step

  1. Combined T Colon/Rectum
  2. Source T
    tmp_combined_t

Next Step

  1. Combined N for Tis Cancers
  2. tmp_combined_n
    Source N

Next Step

  1. Combined M
  2. tmp_combined_m
    tmp_source_m
    Source M

Next Step

  1. Determine Combined Prefix
  2. cmb_t_prefix

Next Step

  1. Determine Combined Prefix
  2. cmb_n_prefix

Next Step

  1. Determine Combined Prefix
  2. cmb_m_prefix

Next Step

  1. Concatenate T
  2. Combined T

Next Step

  1. Concatenate N
  2. Combined N

Next Step

  1. Concatenate M
  2. Combined M

Next Step

  1. TNM 7 Path Stage Group
  2. Combined Stage Group

End

Outputs

Name Default Value Description NAACCR Item Metadata
Derived Version {{ctx_alg_version}} None None
Derived SEER Clin Stage Group 88 NAACCR #3610
None
None
Derived SEER Path Stage Group 88 NAACCR #3605
None
None
Derived SEER Combined Stage Group 88 NAACCR #3614
None
None
Derived SEER Combined T 88 NAACCR #3616
None
None
Derived SEER Combined N 88 NAACCR #3618
None
None
Derived SEER Combined M 88 NAACCR #3620
None
None
Derived SEER Combined T Source <BLANK> NAACCR #3622
None
None
Derived SEER Combined N Source <BLANK> NAACCR #3624
None
None
Derived SEER Combined M Source <BLANK> NAACCR #3626
None
None