Liver

Primary Site Histology Staging Type
C220 8000-8157, 8162-8169, 8190-9136, 9141-9582, 9700-9701 Summary Stage only
C220 8170-8175 TNM 7 and Summary Stage
C221 8170-8175 Summary Stage only

If you are working with a site/histology that only summary stages and you need to directly code it, please use the SEER Summary Stage 2000 manual

Notes

C220 Liver
C221 Intrahepatic bile duct

Note 1: This schema is based on the UICC chapter Liver-Hepatocellular Carcinoma pages 110-113.

  • Primary site C221 with histologies 8170-8175 is not listed in this chapter of the UICC manual; however, it is included in this schema, but is not TNM staged

Note 2: For primary site C220 and cholangiocarcinoma histologies (M-8160, 8161, and 8180), see the Bile DuctsIntraHepat schema.

Note 3: Although the presence of cirrhosis is an important prognostic factor, it does not affect the TNM classification, being an independent prognostic variable.

Note 4: In addition to directly assigning TNM, Summary Stage 2000 (SS2000) must be captured. If directly assigning SS2000, use the Liver and Intrahepatic Bile Ducts chapter on page 108 of the SS2000 on-line manual.

Main Data Items

Name Default Value Used for Staging NAACCR Item Required By Metadata
Clinical T <BLANK> Yes NAACCR #940 None
Clinical N <BLANK> Yes NAACCR #950 None
Clinical M <BLANK> Yes NAACCR #960 None
TNM Clin Stage Group 99 Yes NAACCR #970 None
Pathologic T <BLANK> Yes NAACCR #880 None
Pathologic N <BLANK> Yes NAACCR #890 None
Pathologic M <BLANK> Yes NAACCR #900 None
TNM Path Stage Group 99 Yes NAACCR #910 None
SSF1: Alpha Fetoprotein (AFP) Interpretation 999 No NAACCR #2880 CCCR/Canada
COC
SEER
None
SSF2: Fibrosis Score 988 No NAACCR #2890 CCCR/Canada
COC
None
SSF3: Alpha Fetoprotein (AFP) Lab Value 988 No NAACCR #2900 CCCR/Canada
COC
None
SSF4: Creatinine Value 988 No NAACCR #2910 CCCR/Canada
COC
None
SSF5: Creatinine Unit of Measure 988 No NAACCR #2920 CCCR/Canada
COC
None
SSF6: Total Bilirubin Value 988 No NAACCR #2930 CCCR/Canada
COC
None
SSF7: Total Bilirubin Unit of Measure 988 No NAACCR #2861 CCCR/Canada
COC
None
SSF8: International Normalized Ratio for Prothrombin Time (INR) 988 No NAACCR #2862 CCCR/Canada
COC
None

Additional Data Items

Name Default Value Used for Staging NAACCR Item Required By Metadata
Year of Diagnosis <BLANK> No NAACCR #390 None
Primary Site <BLANK> Yes NAACCR #400 None
Histology <BLANK> Yes NAACCR #522 None
RX Summ Systemic/Surgery Sequence <BLANK> Yes NAACCR #1639 None
RX Summ Surgery/Radiation Sequence <BLANK> Yes NAACCR #1380 None
Regional Nodes Positive <BLANK> Yes NAACCR #820 None