Clinical T

This input is used for staging

Notes

**Note 1:** Involvement of or extension to bone includes any type of tumor extension to the bone, such as erosion, invasion, extension, penetration, or destruction. **Note 2:** Assign T3 for Base of Skull, NOS when there is no information available for more specific bony structures in the skull.

NAACCR Item

NAACCR #940
Clinical T Clinical T Display Description Registrar Notes
cX cTX Primary tumor cannot be assessed Clinical classification criteria met, evaluation done:
Physician unable to assess T
Extension cannot be determined
Physician assigns cTX, no other information available to determine T
c0 cT0 No evidence of primary tumor No evidence of primary tumor
pIS pTis Carcinoma in situ Intraepithelial, noninvasive

Stated as Tis
c1 cT1 Tumor limited to the mucosa with no erosion or destruction of bone Invasive tumor confined to mucosa of maxillary sinus (antrum) WITHOUT erosion or destruction of bone

Localized, NOS

Stated as T1
c2 cT2 Tumor causing bone erosion or destruction, including extension into:
Hard palate
Middle nasal meatus

EXCEPT extension to posterior wall of maxillary sinus and pterygoid plates
Tumor causing bone erosion or destruction
EXCLUDING extension to:
Posterior wall of maxillary sinus (see code 600)
Pterygoid plates (see code 680)
INCLUDING:
Palatine bone, hard palate
Middle nasal meatus
Nasal cavity (floor, lateral wall, septum, turbinates)

Stated as T2
c3 cT3 Tumor invades any of the following:
Bone of posterior wall of maxillary sinus
Subcutaneous tissues
Floor or medial wall of orbit
Pterygoid fossa
Ethmoid sinuses
Ethmoid sinus, anterior
Floor or posterior wall of maxillary sinus
Maxilla, NOS

Ethmoid sinus, posterior
Ethmoid sinus, NOS

Stated as T3
c4 cT4 Not defined by UICC*# Note: T4 has subcategories of T4a and T4b. Assign T4 only when there is no information available to assign one of the subcategories

Tumor invades bone,‚Äč nerve or extrinsic deep muscles

Stated as T4[NOS]
c4A cT4a Tumor invades any of the following:
Anterior orbital contents
Skin of cheek
Pterygoid plates
Infratemporal fossa
Cribriform plate
Sphenoid or frontal sinuses
Anterior orbital contents
Base of skull, NOS
Cribriform plate
Infratemporal fossa
Frontal sinus
Pterygoid plates
Skin of cheek
Sphenoid sinus

Stated as T4a
c4B cT4b Tumor invades any of the following:
Orbital apex
Dura
Brain
Middle cranial fossa
Cranial nerves other than maxillary division of trigeminal nerve (V2)
Nasopharynx
Clivus
Pterygomaxillary fossa
Soft palate
Temporal fossa

Further contiguous extension

Stated as T4b
88 88 Not applicable Primary site/histology not TNM defined
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Clinical classification criteria not met
Clinical classification criteria met, evaluation done:
No information about diagnostic workup
Results not documented in record
Clinical evaluation of primary tumor not done or unknown if done
Tumor first detected on surgical resection (no clinical workup)
Evidence of metastatic disease [(cM1) or (pM1)], no other workup
Only Clinical Stage Group documented (no T, N, or M information available)
\* T4 [NOS] is not defined by UICC in the 7th edition. Approval has been provided by UICC to use "Tumor invades bone, nerve or extrinsic deep muscles" as T4 [NOS]. \# T4 [NOS] is not defined in AJCC 7th edition.