Clinical T

This input is used for staging

Notes

**Note 1:** Assign 88 for in situ cases (behavior code /2). TNM does not include an in situ category for iris tumors. **Note 2:** Ciliary body and Iris are both included in the ICD-O-3 site code of C694, but they are staged with different criteria by TNM. * The Schema Discriminator is used to select the schema appropriate for coding extension for melanoma of the iris **Note 3:** Melanomas of the uvea arise most commonly in the choroid, less frequently in the ciliary body, and least often in the iris. Melanomas of the iris tend to be small, and those arising from or extending to the ciliary body typically are large. **Note 4:** Iris melanomas originate from, and are predominantly located in, this region of the uvea. If less than one-half of the tumor volume is located within the iris, the tumor may have originated in the ciliary body and evaluation should be given to classifying it accordingly. (1)

NAACCR Item

NAACCR #940
Clinical T Clinical T Display Description Registrar Notes
cX cTX Primary tumor cannot be assessed Clinical classification criteria met, evaluation done:
Physician unable to assess T
Extension cannot be determined
Physician assigns cTX, no other information available to determine T
c0 cT0 No evidence of primary tumor
c1 cT1 Tumor limited to iris Note: T1 has subcategories of T1a, T1b and T1c. Assign T1only when there is no information available to assign one of the subcategories

Localized, NOS

Stated as T1 [NOS]
c1A cT1a Not more than 3 clock hours in size Limited to iris not more than 3 clock hours in size
WITHOUT melanomalytic (secondary) glaucoma, or not stated if melanomalytic (secondary) glaucoma

Stated as T1a
c1B cT1b More than 3 clock hours in size Limited to iris more than 3 clock hours in size
WITHOUT melanomalytic (secondary) glaucoma, or not stated if melanomalytic (secondary) glaucoma

Stated as T1b
c1C cT1c WITH secondary glaucoma Limited to iris WITH melanomalytic (secondary) glaucoma

Stated as T1c
c2 cT2 Tumor confluent WITH or extending into:
Ciliary body, choroid or both
Tumor confluent with or extending into the ciliary body and/or choroid
WITHOUT melanomalytic (secondary) glaucoma, or not stated if melanomalytic (secondary) glaucoma

Stated as T2 [NOS]
c2A cT2a WITH secondary glaucoma Tumor confluent with or extending into the ciliary body and/or choroid
WITH melanomalytic (secondary) glaucoma

Stated as T2a
c3 cT3 Tumor confluent WITH or extending into:
Ciliary body, choroid or both, WITH scleral extension
Tumor confluent with or extending into the ciliary body and/or choroid WITH scleral extension
WITHOUT melanomalytic (secondary) glaucoma, or not stated if melanomalytic (secondary) glaucoma

Stated as T3 [NOS]
c3A cT3a With secondary glaucoma Tumor confluent with or extending into the ciliarybody and/or choroid WITH scleral extension
WITH melanomalytic (secondary) glaucoma

Stated as T3a
c4 cT4 Tumor extrascleral extension Note: T4 has subcategories of T4a and T4b. Assign T4 only when there is no information available to assign one of the subcategories

Extrascleral (extraocular) extension, measurement of diameter not specified

Stated as T4 [NOS]
c4A cT4a Less than or equal to 5 mm in diameter Tumor with extrascleral (extraocular) extension less than or equal to 5 mm in diameter

Stated as T4a
c4B cT4b More than 5 mm in diameter Tumor with extrascleral (extraocular) extension greater than 5 mm in diameter

Further contiguous extension

Stated as T4b
88 88 Not applicable In situ case but no pTis is defined by TNM
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Clinical classification criteria not met
Clinical classification criteria met, evaluation done:
No information about diagnostic workup
Results not documented in record
Clinical evaluation of primary tumor not done or unknown if done
Tumor first detected on surgical resection (no clinical workup)
Evidence of metastatic disease [(cM1) or (pM1)], no other workup
Only Clinical Stage Group documented (no T, N, or M information available)
(1) International Union Against Cancer (UICC) *TNM Classification of Malignant Tumors,* 7th ed., Sobin, LH, Gospodarowicz, M, Wittekind, CH, eds. New York: Wiley, 2009, pg., 285