Pathologic N

This input is used for staging


**Note 1:** Histological examination of a regional lymphadenectomy specimen will ordinarily include 6 or more lymph nodes. If the lymph nodes are negative, but the number ordinarily examined is not met, classify as pN0. (1) **Note 2:** Code only regional nodes and nodes, NOS, in this field. Distant nodes are coded in M (distant metastasis). **Note 3:** UICC only has a N2, while AJCC has N2a, N2b, and N2c. If a record comes in with N2a, N2b, or N2c, reassign it to N2. N2 and the subcategories of N2 all stage the same way. **Note 4:** Size of the largest metastasis in a lymph node must be known to assign N. You may use a physician’s statement of the N category if this is the only information in the medical record. * If the size of the metastasis is not documented, determine the size of the largest involved lymph node as documented pathologically * If the size of the lymph node(s) cannot be determined, assign N1 * Do not code the size of any node(s) assigned in M (distant metastasis) **Regional lymph nodes** Iliac, NOS External Internal (hypogastric), NOS Obturator Inguinal, NOS Deep inguinal, NOS Node of Cloquet or Rosenmuller (highest deep inguinal) Superficial inguinal (femoral) Regional lymph node, NOS Lymph nodes, NOS


Pathologic N Pathologic N Display Description Registrar Notes
pX pNX Regional lymph nodes cannot be assessed Pathologic classification criteria met, evaluation done:
Physician unable to assess N
Surgical resection primary tumor, no regional lymph nodes removed
Involvement of regional lymph nodes not documented
Physician assigns pNX, no other information available to determine N
p0 pN0 No regional lymph node metastasis
p1 pN1 Metastasis in a single lymph node, 3 cm or less in greatest dimension IPSILATERAL positive regional lymph node(s), not stated if single or multiple

Positive lymph nodes, not stated if ipsilateral, contralateral or bilateral

Stated as N1
p2 pN2 Metastasis in a single lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple lymph nodes, none more than 6 cm in greatest dimension* Multiple ipsilateral lymph nodes, NOS
Bilateral or contralateral lymph nodes, NOS

Stated as N2 (N2a, N2b, N2c, N2 [NOS])
p3 pN3 Metastasis in a lymph node, more than 6 cm in greatest dimension Stated as N3
c0 cN0 Clinically: No regional lymph node metastasis Use only for TNM defined pTis cases where there is a resection of the primary and the nodes are not evaluated pathologically
88 88 Not applicable Primary site/histology not TNM defined
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Pathologic classification criteria not met
No surgical resection of primary tumor and there isn’t a positive biopsy of a structure in the highest T category and highest N category
Evidence of metastatic disease (pM1), no other workup
Only Pathologic Stage Group documented (no T, N, or M information available)
(1) International Union Against Cancer (UICC) *TNM Classification of Malignant Tumors,* 7th ed., Sobin, LH, Gospodarowicz, M, Wittekind, CH, eds. New York: Wiley, 2009, pg., 167 \* For this schema, UICC has only the N2 subcategory. AJCC has subcategories N2a, N2b, or N2c.