Pathologic T

This input is used for staging


**Note 1:** TNM defines Tis as carcinoma in situ/dysplasia (tumor size less than 0.5 mm), confined to mucosa. Neuroendocrine tumors (NET) stated to be in situ, noninvasive, or confined to mucosa are classified as Tis. * "Dysplasia" alone is generally not reportable in cancer registries but, if a registry does collect it, assign Tis **Note 2:** Intraluminal or intramural extension to esophagus and duodenum is classified by the depth of greatest invasion. * For extension to esophagus or duodenum via serosa, assign T4 **Note 3:** Tumor size must be known to assign a value of T1 or T2. You may use a physician’s statement of the T category if this is the only information in the medical record. * If the tumor appears to be in the T1 or T2 categories, but no size or category is specified, assign TX **Note 4:** Assign the appropriate T category (T1, T2) based on the tumor size for the following descriptions Invasion into Lamina propria, including lamina propria in a polyp Muscularis mucosae, including muscularis mucosae in a polyp Submucosa (superficial invasion), including submucosa in a polyp Implants inside stomach Confined to stomach Localized, NOS


Pathologic T Pathologic T Display Description Registrar Notes
pX pTX Primary tumor cannot be assessed Pathologic classification criteria met, evaluation done:
Physician unable to assess T
Surgical resection of primary tumor, extension not stated
Tumor size (TS) unknown for T categories where TS needed to determine T
Physician assigns pTX, no other information available to determine T
p0 pT0 No evidence of primary tumor
pIS pTis Carcinoma in situ/dysplasia (tumor less than 0.5 mm, confined to mucosa) Intraepithelial, noninvasive
Tumor size less than 0.5 millimeters (mm)
Tumor confined to mucosa, NOS including intramucosal, NOS

Stated as Tis
p1 pT1 Tumor confined to mucosa and 0.5 mm or more but not greater than 1 cm in size; OR

Invades submucosa and is no greater than 1 cm in greatest dimension
Stated as T1
p2 pT2 Tumor invades muscularis propria OR

Is more than 1 cm in greatest dimension
Stated as T2
p3 pT3 Tumor invades subserosa Invasion through muscularis propria or muscularis, NOS
Extension through wall, NOS
Perimuscular tissue invaded
Subserosa/(sub)serosal fat penetrated

Extension to adjacent (connective) tissue
WITHOUT perforation of visceral peritoneum:
Gastric artery
Perigastric fat

Stated as T3
p4 pT4 Tumor perforates visceral peritoneum (serosa) or other organs or adjacent structures Invasion of/through serosa (mesothelium) (tunica serosa) (visceral peritoneum)
Including perforation of visceral peritoneum covering the gastric ligaments or the omentum
WITHOUT invasion of adjacent structures

Abdominal wall
Adrenal gland
Celiac axis
Duodenum via serosa or NOS
Esophagus via serosa
Small intestine, NOS
Transverse colon/mesocolon (including flexures)

Further contiguous extension

Stated as T4
88 88 Not applicable Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Pathologic classification criteria not met
Pathologic classification criteria met, evaluation done:
Results not documented in patient record
No surgical resection of known primary tumor (not T0)
Resection insufficient for site-specific pathologic assessment
No surgical resection of primary tumor and there isn’t a positive biopsy of a structure in the highest T category and highest N category
Evidence of metastatic disease (pM1), no other workup
Only Pathologic Stage Group documented (no T, N, or M information available)