Pathologic T

This input is used for staging

Notes

**Note 1:** Assign 88 for in situ cases (behavior code /2). TNM does not include an in situ category for choroid tumors. **Note 2:** Melanomas of the uvea arise most commonly in the choroid, less frequently in the ciliary body, and least often in the iris. Melanomas of the iris tend to be small, and those arising from or extending to the ciliary body typically are large. **Note 3:** UICC 7th Edition assigns a T value to combinations of measurements for basal diameter and thickness of tumor divided into four Tumor Size Categories in a charted format. (1) **Note 4:** In clinical practice, the largest tumor basal diameter may be estimated in optic disc diameters (dd, average: 1 dd = 1.5 mm). Tumor thickness may be estimated in diopters (average: 2.5 diopters = 1 mm). However, techniques such as ultrasonography and fundus photography are used to provide more accurate measurements. Ciliary body involvement can be evaluated by the slit-lamp, opthalmoscopy, gonioscopy and transillumination. However, high frequency ultrasonography (ultrasound biomicroscopy) is used for more accurate assessment. Extension through the sclera is evaluated visually before and during surgery, and with ultrasonography, computed tomography or magnetic resonance imaging. (1) **Note 5:** When histopathological measurements are recorded after fixation, tumor diameter and thickness may be underestimated because of tissue shrinkage. (1)

NAACCR Item

NAACCR #880
Pathologic T Pathologic T Display Description Registrar Notes
pX pTX Primary tumor cannot be assessed Basal diameter and thickness not known
Tumor size category not known

Pathologic classification criteria met, evaluation done:
Physician unable to assess T
Surgical resection of primary tumor, extension not stated
Physician assigns pTX, no other information available to determine T
p0 pT0 No evidence of primary tumor
p1 pT1 Tumor size category 1 Note: T1 has subcategories of T1a, T1b, T1c and T1d. Assign T1 only when there is no information available to assign one of the subcategories

Tumor Size Category 1
Localized, NOS

Stated as T1 [NOS]
p1A pT1a WITHOUT ciliary body involvement and extraocular extension Tumor WITHOUT ciliary body involvement WITHOUT extraocular extension OR ciliary body involvement and extraocular extension not stated

AND stated as Tumor Size Category 1

Stated as T1a
p1B pT1b WITH ciliary body involvement Tumor WITH ciliary body involvement WITHOUT extraocular extension OR extraocular extension not stated

AND stated as Tumor Size Category 1

Stated as T1b
p1C pT1c WITHOUT ciliary body involvement but
WITH extraocular extension less than or equal to 5 mm in diameter
Tumor WITHOUT ciliary body involvement OR ciliary involvement not stated
WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 1

Stated as T1c
p1D pT1d WITH ciliary body involvement AND
Extraocular extension less than or equal to 5 mm in diameter
Tumor WITH ciliary body involvement WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 1

Stated as T1d
p2 pT2 Tumor size category 2 Note: T2 has subcategories of T2a, T2b, T2c and T2d. Assign T2 only when there is no information available to assign one of the subcategories

Tumor Size Category 2

Stated as T2 [NOS]
p2A pT2a WITHOUT ciliary body involvement and extraocular extension Tumor WITHOUT ciliary body involvement WITHOUT extraocular extension OR ciliary body involvement and extraocular extension not stated

AND stated as Tumor Size Category 2

Stated as T2a
p2B pT2b WITH ciliary body involvement Tumor WITH ciliary body involvement WITHOUT extraocular extension OR extraocular extension not stated

AND stated as Tumor Size Category 2

Stated as T2b
p2C pT2c WITHOUT ciliary body involvement but
WITH extraocular extension less than or equal to 5 mm in diameter
Tumor WITHOUT ciliary body involvement OR ciliary involvement not stated
WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 2

Stated as T2c
p2D pT2d WITH ciliary body involvement but
WITH extraocular extension less than or equal to 5 mm in diameter
Tumor WITH ciliary body involvement WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 2

Stated as T2d
p3 pT3 Tumor size category 3 Note: T3 has subcategories of T3a, T3b, T3c and T3d. Assign T3 only when there is no information available to assign one of the subcategories

Tumor Size Category 3

Stated as T3 [NOS]
p3A pT3a WITHOUT ciliary body involvement and extraocular extension Tumor WITHOUT ciliary body involvement WITHOUT extraocular extension OR ciliary body involvement and extraocular extension not stated

AND stated as Tumor Size Category 3

Stated as T3a
p3B pT3b WITH ciliary body involvement Tumor WITH ciliary body involvement WITHOUT extraocular extension OR extraocular extension not stated

AND stated as Tumor Size Category 3

Stated as T3b
p3C pT3c WITHOUT ciliary body involvement but
WITH extraocular extension less than or equal to 5 mm in diameter
Tumor WITHOUT ciliary body involvement OR ciliary involvement not stated
WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 3

Stated as T3c
p3D pT3d WITH ciliary body involvement but
WITH extraocular extension less than or equal to 5 mm in diameter
Tumor WITH ciliary body involvement WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 3

Stated as T3d
p4 pT4 Tumor size category 4 Note: T4 has subcategories of T4a, T4b, T4c, T4d and T4e. Assign T4 only when there is no information available to assign one of the subcategories

Tumor Size Category 4

Further contiguous extension

Stated as T4 [NOS]
p4A pT4a WITHOUT ciliary body involvement and extraocular extension Tumor WITHOUT ciliary body involvement WITHOUT extraocular extension OR ciliary body involvement and extraocular extension not stated

AND stated as Tumor Size Category 4

Stated as T4a
p4B pT4b WITH ciliary body involvement Tumor WITH ciliary body involvement WITHOUT extraocular extension OR extraocular extension not stated

AND stated as Tumor Size Category 4

Stated as T4b
p4C pT4c WITHOUT ciliary body involvement but
WITH extraocular extension less than or equal to 5 mm in diameter
Tumor WITHOUT ciliary body involvement OR ciliary involvement not stated
WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 4

Stated as T4c
p4D pT4d WITH ciliary body involvement but
WITH extraocular extension less than or equal to 5 mm in diameter
Tumor WITH ciliary body involvement WITH extraocular extension less than or equal to 5 mm in diameter OR extraocular extension diameter not stated

AND stated as Tumor Size Category 4

Stated as T4d
p4E pT4e Any tumor size category with extraocular extension more than 5 mm in diameter Tumor WITH extraocular extension greater than 5 mm in diameter

AND stated as Tumor Size Category 4

Stated as T4e
88 88 Not applicable In situ case but no pTis is defined by TNM
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Pathologic classification criteria not met
Pathologic classification criteria met, evaluation done:
Results not documented in patient record
No surgical resection of known primary tumor (not T0)
Resection insufficient for site-specific pathologic assessment
No surgical resection of primary tumor and there isn’t a positive biopsy of a structure in the highest T category and highest N category
Evidence of metastatic disease (pM1), no other workup
Only Pathologic Stage Group documented (no T, N, or M information available)
(1) International Union Against Cancer (UICC) *TNM Classification of Malignant Tumors,* 7th ed., Sobin, LH, Gospodarowicz, M, Wittekind, CH, eds. New York: Wiley, 2009, pgs., 285, 286, 288