Pathologic N

This input is used for staging

Notes

Note 1: Histological examination of a regional lymphadenectomy specimen will ordinarily include 6 or more lymph nodes. If the lymph nodes are negative, but the number ordinarily examined is not met, classify as pN0. (1)

Note 2: Code only regional nodes and nodes, NOS, in this field. Distant nodes are coded in M (distant metastasis).

Note 3: Pericholedochal (common bile duct) lymph nodes are coded in N (regional lymph nodes) for primaries of the duodenum. They are coded in M (distant metastasis) for primaries of other small intestine subsites.

Regional lymph nodes

Duodenum primaries (C170)

Duodenal
Gastroduodenal
Hepatic
Pancreaticoduodenal
Pericholodochal (common bile duct)
Pyloric: infrapyloric, subpyloric
Superior mesenteric

Jejunum primaries (C171)

 Mesenteric, NOS
 Superior mesenteric

Ileum primaries (C172)

 Cecal (anterior, posterior, retrocecal) 
 Ileocecal       
 Mesenteric, NOS
 Superior mesenteric

NAACCR Item

NAACCR #890
Pathologic N Pathologic N Display Description Registrar Notes
pX pNX Regional lymph nodes cannot be assessed# Pathologic classification criteria met, evaluation done:
Physician unable to assess N
Surgical resection primary tumor, no regional lymph nodes removed
Involvement of regional lymph nodes not documented
Physician assigns pNX, no other information available to determine N
p0 pN0 No regional lymph node metastasis
p1 pN1 Regional lymph node metastasis Regional lymph nodes, NOS
Lymph nodes, NOS

Stated as N1
c0 cN0 Clinically: No regional lymph node metastasis Use only for TNM defined pTis cases where there is a resection of the primary and the nodes are not evaluated pathologically
88 88 Not applicable In situ case but no pTis is defined by TNM
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Pathologic classification criteria not met
No surgical resection of primary tumor and there isn’t a positive biopsy of a structure in the highest T category and highest N category
Evidence of metastatic disease (pM1), no other workup
Only Pathologic Stage Group documented (no T, N, or M information available)

(1) International Union Against Cancer (UICC) TNM Classification of Malignant Tumors, 7th ed., Sobin, LH, Gospodarowicz, M, Wittekind, CH, eds. New York: Wiley, 2009, pg., 84

# NX is not defined in AJCC 7th edition.