Clinical T
This input is used for staging
Notes
**Note 1:** "Multiple (satellite) nodules/tumors" include satellitosis, multifocal tumors, and intrahepatic metastases. **Note 2:** Major vascular invasion is defined as invasion of the branches of the main portal vein (right or left portal vein, not including sectoral or segmental branches) or as invasion of one or more of the three hepatic veins (right, middle, or left). Invasion of the hepatic artery or vena cava is assigned T3. **Note 3:** Cholangiocarcinoma may be classified by growth pattern. The tumor growth patterns of intrahepatic cholangiocarcinoma include the mass forming type, the periductal infiltrating type, and a mixed type. The periductal infiltrating type of cholangiocarcinoma demonstrates a diffuse longitudinal growth pattern along the bile duct. Limited analyses suggest that the diffuse periductal infiltrating type is associated with a poor prognosis. The presence of periductal invasion is assigned T4.NAACCR Item
NAACCR #940| Clinical T | Clinical T Display | Description | Registrar Notes |
|---|---|---|---|
| cX | cTX | Primary tumor cannot be assessed | Clinical classification criteria met, evaluation done: Physician unable to assess T Extension cannot be determined Physician assigns cTX, no other information available to determine T |
| c0 | cT0 | No evidence of primary tumor | |
| pIS | pTis | Carcinoma in situ (intraductal tumor) | Intraepithelial, noninvasive Stated as Tis |
| c1 | cT1 | Solitary tumor without vascular invasion | Single lesion in one lobe of liver WITHOUT intrahepatic vascular invasion OR vascular invasion not stated Single lesion in more than one lobe of liver (contiguous growth) WITHOUT vascular invasion OR vascular invasion not stated Extension to gallbladder WITH or WITHOUT single lesion in one or more lobes of liver (contiguous growth) WITHOUT vascular invasion OR vascular invasion not stated Confined to liver, NOS Localized, NOS Stated as T1 |
| c2 | cT2 | Not defined by UICC*# | Note: T2 has subcategories of T2a and T2b. Assign T2 only when there is no information available to assign one of the subcategories. Multiple tumors or single tumor with vascular invasion Stated as T2[NOS] |
| c2A | cT2a | Solitary tumor with vascular invasion | Single lesion in one lobe of liver WITH intrahepatic vascular invasion Single lesion in more than one lobe of liver (contiguous growth) WITH vascular invasion WITH or WITHOUT vascular invasion plus extension to gallbladder Single tumor WITH major vascular invasion: major branch(es) of portal or hepatic vein(s) WITH or WITHOUT extension to gallbladder Stated as T2a |
| c2B | cT2b | Multiple tumors, with or without vascular invasion | Multiple (satellite) nodules/tumors in one lobe of liver: WITH or WITHOUT intrahepatic vascular invasion plus extension to gallbladder OR WITH major vascular invasion: major branch(es) of portal or hepatic vein(s) OR WITH major vascular invasion and extension to gallbladder Multiple (satellite) nodules/tumors in more than one lobe of liver Satellite nodules, NOS Stated as T2b |
| c3 | cT3 | Tumor perforates the visceral peritoneum OR Directly invades adjacent extrahepatic structures |
Diaphragm Direct extension/perforation of visceral peritoneum Extension to hepatic artery or vena cava Extrahepatic bile ducts WITH or WITHOUT satellite nodules in more than one lobe or multiple tumors with major vascular invasion Multiple (satellite) nodules on surface of liver parenchyma Lesser omentum Ligament(s): Coronary Falciform Hepatoduodenal Hepatogastric Round (of liver) Triangular Parietal peritoneum Further contiguous extension: Pancreas Pleura Stomach Other contiguous extension Stated as T3 |
| c4 | cT4 | Tumor with periductal invasion (periductal growth pattern) | Stated as T4 |
| 88 | 88 | Not applicable | Primary site/histology not TNM defined Death certificate only (DCO) case |
| <BLANK> | BLANK | See Registrar Notes | Clinical classification criteria not met Clinical classification criteria met, evaluation done: No information about diagnostic workup Results not documented in record Clinical evaluation of primary tumor not done or unknown if done Tumor first detected on surgical resection (no clinical workup) Evidence of metastatic disease [(cM1) or (pM1)], no other workup Only Clinical Stage Group documented (no T, N, or M information available) |