Pathologic T
This input is used for staging
Notes
**Note 1:** High grade dysplasia and severe dysplasia of the colon are generally not reportable in cancer registries. * Assign pTis if your registry collects these tumors **Note 2:** In situ includes cancer cells confined within the glandular basement membrane (intraepithelial); localized includes confined to lamina propria (intramucosal), the muscular mucosa, and muscularis propria. **Note 3:** Ignore intraluminal extension to adjacent segment(s) of colon/rectum or to the ileum from the cecum; code depth of invasion or extracolonic spread as indicated. **Note 4:** Direct invasion in cT4b includes invasion of other organs or segments of the colorectum by way of the serosa, as confirmed on microscopic examination, or for tumors in a retroperitoneal or subperitoneal location, direct invasion of other organs or structures by virtue of extension beyond the muscularis propria. **Note 5:** Tumor that is adherent to other organs or structures, macroscopically, is classified T4b. However, if no tumor is present in the adhesion, microscopically, the classification should be pT1 - pT3. **Note 6:** Assign T4b for contiguous extension from the site of origin. Discontinuous involvement is coded in M (distant metastasis).NAACCR Item
NAACCR #880| Pathologic T | Pathologic T Display | Description | Registrar Notes |
|---|---|---|---|
| pX | pTX | Primary tumor cannot be assessed | Pathologic classification criteria met, evaluation done: Physician unable to assess T Surgical resection of primary tumor, extension not stated Physician assigns pTX, no other information available to determine T |
| p0 | pT0 | No evidence of primary tumor | |
| pIS | pTis | Carcinoma in situ: intraepithelial or invasion of lamina propria | (Adeno)carcinoma, noninvasive, in a polyp or adenoma Invasive tumor confined to: Lamina propria, including lamina propria in the stalk of a polyp Mucosa, NOS, including intramucosal, NOS Muscularis mucosae (but not through), including muscularis mucosae in the stalk of a polyp Stated as Tis |
| p1 | pT1 | Tumor invades submucosa | Confined to: Head of polyp, NOS Stalk of polyp, NOS Invasive tumor in polyp, NOS Invades submucosa (superficial invasion), including submucosa in the head or stalk of polyp Confined to rectosigmoid, NOS Confined to rectum, NOS Localized, NOS Stated as T1 |
| p2 | pT2 | Tumor invades muscularis propria | For rectum (C209): Tumor invading muscularis propria with intraluminal extension to colon and/or anal canal/anus Stated as T2 |
| p3 | pT3 | Tumor invades subserosa or into non-peritionalized pericolic or perirectal tissues | Extension through wall, NOS Invasion through muscularis propria or muscularis, NOS Perimuscular tissue invaded Subserosal tissue/(sub)serosal fat invaded Transmural, NOS For rectum (C209): Tumor invading through muscularis propria with intraluminal extension to colon and/or anal canal/anus Adjacent (connective) tissue: For all sites: Perirectal fat For rectosigmoid: Mesentery (including mesenteric fat, mesocolon) Pericolic fat For rectum: Rectovaginal septum Fat, NOS Stated as T3 |
| p4 | pT4 | Tumor directly invades other organs or structures and/or perforates visceral peritoneum# | Note: T4 has subcategories of T4a and T4b. Assign T4 only when there is no information available to assign one of the subcategories Stated as T4 [NOS] |
| p4A | pT4a | Tumor perforates visceral peritoneum | Invasion of/through serosa (mesothelium) (visceral peritoneum) Stated as T4a |
| p4B | pT4b | Tumor directly invades other organs or structures | Tumor found in adhesion(s) if microscopic examination performed Adherent to other organs or structures, NOS For both rectum and rectosigmoid sites: Bladder Cul de sac (rectouterine pouch) Ovary(ies) Pelvic wall/pelvic plexuses Prostate Skeletal muscle of pelvic floor Uterus Vagina For rectosigmoid (C199): Small intestine Colon via serosa Fallopian tube(s) Ureter(s) For rectum (C209): Anal canal/anus extraluminally Bone(s) of pelvis Cervix Ductus deferens Perineum, perianal skin Rectovesical fascia for males only Sacrum Sacral plexus Seminal vesicle(s) Urethra Further contiguous extension Stated as T4b |
| 88 | 88 | Not applicable | Primary site/histology not TNM defined Death certificate only (DCO) case |
| <BLANK> | BLANK | See Registrar Notes | Pathologic classification criteria not met Pathologic classification criteria met, evaluation done: Results not documented in patient record No surgical resection of known primary tumor (not T0) Resection insufficient for site-specific pathologic assessment No surgical resection of primary tumor and there isn’t a positive biopsy of a structure in the highest T category and highest N category Evidence of metastatic disease (pM1), no other workup Only Pathologic Stage Group documented (no T, N, or M information available) |