Clinical T

This input is used for staging


**Note 1:** TNM defines Tis as carcinoma in situ/dysplasia (tumor size less than 0.5 mm), confined to mucosa. Neuroendocrine tumors (NET) stated to be in situ, noninvasive, or confined to mucosa are classified as Tis. * "Dysplasia" alone is generally not reportable in cancer registries but, if a registry does collect it, assign Tis **Note 2:** Intraluminal or intramural extension to esophagus and duodenum is classified by the depth of greatest invasion. * For extension to esophagus or duodenum via serosa, assign T4 **Note 3:** Tumor size must be known to assign a value of T1 or T2. You may use a physician’s statement of the T category if this is the only information in the medical record. * If the tumor appears to be in the T1 or T2 categories, but no size or category is specified, assign TX **Note 4:** Assign the appropriate T category (T1, T2) based on the tumor size for the following descriptions Invasion into Lamina propria, including lamina propria in a polyp Muscularis mucosae, including muscularis mucosae in a polyp Submucosa (superficial invasion), including submucosa in a polyp Implants inside stomach Confined to stomach Localized, NOS


Clinical T Clinical T Display Description Registrar Notes
cX cTX Primary tumor cannot be assessed Clinical classification criteria met, evaluation done:
Physician unable to assess T
Extension cannot be determined
Tumor size (TS) unknown for T categories where TS needed to determine T
Physician assigns cTX, no other information available to determine T
c0 cT0 No evidence of primary tumor
pIS pTis Carcinoma in situ/dysplasia (tumor less than 0.5 mm, confined to mucosa) Intraepithelial, noninvasive
Tumor size less than 0.5 millimeters (mm)
Tumor confined to mucosa, NOS including intramucosal, NOS

Stated as Tis
c1 cT1 Tumor confined to mucosa and 0.5 mm or more but not greater than 1 cm in size; OR

Invades submucosa and is no greater than 1 cm in greatest dimension
Stated as T1
c2 cT2 Tumor invades muscularis propria OR

Is more than 1 cm in greatest dimension
Stated as T2
c3 cT3 Tumor invades subserosa Invasion through muscularis propria or muscularis, NOS
Extension through wall, NOS
Perimuscular tissue invaded
Subserosa/(sub)serosal fat penetrated

Extension to adjacent (connective) tissue
WITHOUT perforation of visceral peritoneum:
Gastric artery
Perigastric fat

Stated as T3
c4 cT4 Tumor perforates visceral peritoneum (serosa) or other organs or adjacent structures Invasion of/through serosa (mesothelium) (tunica serosa) (visceral peritoneum)
Including perforation of visceral peritoneum covering the gastric ligaments or the omentum
WITHOUT invasion of adjacent structures

Abdominal wall
Adrenal gland
Celiac axis
Duodenum via serosa or NOS
Esophagus via serosa
Small intestine, NOS
Transverse colon/mesocolon (including flexures)

Further contiguous extension

Stated as T4
88 88 Not applicable Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Clinical classification criteria not met
Clinical classification criteria met, evaluation done:
No information about diagnostic workup
Results not documented in record
Clinical evaluation of primary tumor not done or unknown if done
Tumor first detected on surgical resection (no clinical workup)
Evidence of metastatic disease [(cM1) or (pM1)], no other workup
Only Clinical Stage Group documented (no T, N, or M information available)