Clinical M

This input is used for staging

NAACCR Item

NAACCR #960
Clinical M Clinical M Display Description Registrar Notes
c0 cM0 No distant metastasis Unknown; distant metastasis not stated
Distant metastasis cannot be assessed
Not documented in patient record
c1 cM1 Distant metastasis# CLINICAL assessment only:
Note: M1 has subcategories of M1a, M1b and M1c. Assign M1 only when there is no information available to assign one of the subcategories

Distant metastasis, NOS

Stated as M1 [NOS]
c1A cM1a Skin, subcutaneous tissue or lymph node(s) beyond the regional lymph nodes CLINICAL assessment only:
Metastasis to skin or subcutaneous tissue beyond nodes WITH or WITHOUT distant nodes

Metastasis to underlying cartilage, bone, skeletal muscle (excluding direct extension) WITH or WITHOUT distant nodes

Distant lymph nodes, NOS
Nodes in contiguous (secondary) and bidirectional (cephalad/caudal) primary nodal basins

Stated as M1a
c1B cM1b Lung CLINICAL assessment only:
Metastasis to lung WITH or WITHOUT distant nodes

Stated as M1b
c1C cM1c Other sites, or any site with elevated serum lactic dehydrogenase (LDH) CLINICAL assessment only:
Metastasis to all other visceral or distant sites WITH or WITHOUT metastasis to lungs

Metastasis to all other visceral or distant sites plus distant nodes WITH or WITHOUT metastasis to lungs

Any distant metastasis with elevated serum lactic dehydrogenases

Carcinomatosis

Stated as M1c
p1 pM1 Distant metastasis# HISTOLOGICALLY confirmed:
Note: M1 has subcategories of M1a, M1b and M1c. Assign M1 only when there is no information available to assign one of the subcategories

Distant metastasis, NOS
p1A pM1a Skin, subcutaneous tissue or lymph node(s) beyond the regional lymph nodes HISTOLOGICALLY confirmed:
Metastasis to skin or subcutaneous tissue beyond nodes WITH or WITHOUT distant nodes

Metastasis to underlying cartilage, bone, skeletal muscle (excluding direct extension) WITH or WITHOUT distant nodes

Distant lymph nodes, NOS
Nodes in contiguous (secondary) and bidirectional (cephalad/caudal) primary nodal basins
p1B pM1b Lung HISTOLOGICALLY confirmed:
Metastasis to lung WITH or WITHOUT distant nodes
p1C pM1c Other sites, or any site with elevated serum lactic dehydrogenase (LDH) HISTOLOGICALLY confirmed:
Metastasis to all other visceral or distant sites WITH or WITHOUT metastasis to lungs

Metastasis to all other visceral or distant sites plus distant nodes WITH or WITHOUT metastasis to lungs

Any distant metastasis with elevated serum lactic dehydrogenases

Carcinomatosis
88 88 Not applicable Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Clinical classification criteria not met
Clinical classification criteria met, evaluation done:
No information about diagnostic workup
Results not documented in patient record
Clinical evaluation of T and N not done, no evidence metastatic disease
Tumor first detected on surgical resection (no clinical workup)
Only Clinical Stage Group documented (no T, N, or M information available)
\# M1 [NOS] is not defined in AJCC 7th edition