Site-Specific Factor 18

Disseminated Tumor Cells (DTC) and Method of Detection

Notes

**Note 1:** Disseminated tumor cells (DTCs) are isolated tumor cells (ITCs) (micrometastases less than or equal to 0.2 mm) found in the bone marrow or other nonregional nodal tissues or organs. **Note 2:** Immunohistochemistry (IHC) with cytokeratin stains and Reverse Transcription Polymerase Chain Reaction (RT-PCR) are laboratory methods for identifying very small amounts of tumor cells in tissue. RT-PCR amplifies genetic material identified by probes for tumor genes to a detectable level. **Note 3:** Any positive test takes precedence over a negative or borderline test. Information about a known test takes precedence over no information about other tests.

Default

988

NAACCR Item

NAACCR #2872
Code Description
010 Positive, Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) test
020 Positive, immunohistochemistry (IHC) test
025 Positive on RT-PCR and IHC
030 Positive, other test type
040 Positive, unknown test type
110 Negative/normal, RT-PCR test
120 Negative/normal IHC test
130 Negative/normal, other test type
140 Negative/normal, unknown test type
210 Borderline; equivocal; indeterminate; undetermined if positive or negative, RT-PCR test
220 Borderline; equivocal; indeterminate; undetermined if positive or negative, IHC test
230 Borderline; equivocal; indeterminate; undetermined if positive or negative, other test type
240 Borderline; equivocal; indeterminate; undetermined if positive or negative, unknown test type
988 Not applicable: Information not collected for this case
997 Test ordered, results not in chart
998 Test not done (test not ordered and not performed)
999 Unknown or no information
Not documented in patient record