Clinical T

This input is used for staging


**Note 1:** Assign 88 for in situ cases (behavior code /2). TNM does not include an in situ category for salivary gland other tumors. **Note 2:** Tumor size must be known to assign a value of T1, T2 or T3. You may use a physician’s statement of the T category if this is the only information in the medical record. * If the tumor appears to be in the T1, T2 or T3 categories, but no size or category is specified, assign TX **Note 3:** Assign the appropriate T category (T1, T2 or T3) based on the tumor size for the following descriptions Invasive tumor confined to gland/duct of origin Microscopic extraparenchymal extension ONLY to periglandular soft/connective tissue Confined to salivary gland, NOS Localized, NOS **Note 4:** Extraparenchymal extension is clinical or macroscopic evidence of invasion of soft tissues or nerve, except those listed under T4a and T4b. Microscopic evidence alone does not constitute extraparenchymal extension for classification purposes. **Note 5:** Periosteum is a fibrous membrane that wraps the outer surface of bones. Mucoperiosteum is a compound structure of mucous membrane and periosteum. Cortical bone is the dense compact outer layer of bone.


Clinical T Clinical T Display Description Registrar Notes
cX cTX Primary tumor cannot be assessed Clinical classification criteria met, evaluation done:
Physician unable to assess T
Extension cannot be determined
Tumor size (TS) unknown for T categories where TS needed to determine T
Physician assigns cTX, no other information available to determine T
c0 cT0 No evidence of primary tumor
c1 cT1 Tumor 2 cm or less in greatest dimension
WITHOUT extraparenchymal extension
Stated as T1
c2 cT2 Tumor more than 2 cm but not more than 4 cm in greatest dimension
WITHOUT extraparenchymal extension
Stated as T2
c3 cT3 Tumor more than 4 cm and/or tumor
WITH extraparenchymal extension
Macroscopic extraparenchymal extension to:
Periglandular soft/connective tissue
Another major salivary gland (parotid, submandibular)
Skeletal muscle:

Other extension:
Facial artery or vein
Maxillary artery
Spinal accessory nerve

Stated as T3
c4 cT4 Not defined by UICC*# Note: T4 has subcategories of T4a and T4b. Assign T4 only when there is no information available to assign one of the subcategories

Tumor invades bone, nerve or extrinsic deep muscles

Stated as T4[NOS]
c4A cT4a Tumor invades:
Ear canal
Facial nerve
External auditory meatus
Facial (7th)
Periosteum of mandible

Stated as T4a
c4B cT4b Tumor invades:
Base of skull
Pterygoid plates

OR encases carotid artery
Skull, NOS

Further contiguous extension

Stated as T4b
88 88 Not applicable Primary site/histology not TNM defined
In situ case but no pTis is defined by TNM
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Clinical classification criteria not met
Clinical classification criteria met, evaluation done:
No information about diagnostic workup
Results not documented in record
Clinical evaluation of primary tumor not done or unknown if done
Tumor first detected on surgical resection (no clinical workup)
Evidence of metastatic disease [(cM1) or (pM1)], no other workup
Only Clinical Stage Group documented (no T, N, or M information available)
\* T4 [NOS] is not defined by UICC in the 7th edition. Approval has been provided by UICC to use "Tumor invades bone, nerve or extrinsic deep muscles" as T4 [NOS]. \# T4 [NOS] is not defined in AJCC 7th edition.