Pathologic T

This input is used for staging


**Note:** Ignore extension from gallbladder to cystic duct. Ignore extension to extrahepatic bile ducts or ampulla of Vater (T3) when other structures in T4 are involved.


Pathologic T Pathologic T Display Description Registrar Notes
pX pTX Primary tumor cannot be assessed Pathologic classification criteria met, evaluation done:
Physician unable to assess T
Surgical resection of primary tumor, extension not stated
Physician assigns pTX, no other information available to determine T
p0 pT0 No evidence of primary tumor
pIS pTis Carcinoma in situ Intraepithelial, noninvasive

Stated as Tis
p1 pT1 Tumor invades lamina propria or muscular layer Note: T1 has subcategories of T1a and T1b. Assign T1 only when there is no information available to assign one of the subcategories

Confined to gallbladder, NOS
Localized, NOS

Stated as T1 [NOS]
p1A pT1a Tumor invades lamina propria Invasive tumor confined to:
Lamina propria
Mucosa, NOS
Submucosa (superficial invasion)

Stated as T1a
p1B pT1b Tumor invades muscular layer Muscularis propria

Stated as T1b
p2 pT2 Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver Perimuscular connective tissue

Stated as T2
p3 pT3 Tumor perforates the serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, such as:
Extrahepatic bile ducts
Invasion of/through serosa (visceral peritoneum)

Extension to:
Abdominal wall
Ampulla of Vater
Branch(es) of hepatic artery (right or left) but not into main portal vein or hepatic artery
Branch(es) of portal vein (right or left)
Cystic artery vein
Small intestine

Extension into:

Stated as T3
p4 pT4 Tumor invades main portal vein or hepatic artery or invades two or more extrahepatic organs or structures Extension to:
Common hepatic artery
Main portal vein
Hepatic artery, NOS
Portal vein, NOS

Further contiguous extension

Stated as T4
88 88 Not applicable Primary site/histology not TNM defined
Death certificate only (DCO) case
<BLANK> BLANK See Registrar Notes Pathologic classification criteria not met
Pathologic classification criteria met, evaluation done:
Results not documented in patient record
No surgical resection of known primary tumor (not T0)
Resection insufficient for site-specific pathologic assessment
No surgical resection of primary tumor and there isn’t a positive biopsy of a structure in the highest T category and highest N category
Evidence of metastatic disease (pM1), no other workup
Only Pathologic Stage Group documented (no T, N, or M information available)