Clinical M
This input is used for staging
Notes
**Note 1:** Distant lymph node involvement is coded as N2 for TNM staging for retinoblastoma and is collected in M (distant metastasis). **Note 2:** Code single and multiple metastatic lesions in this field based on the presentation of metastases in all distant sites excluding distant lymph nodes. **Note 3:** Metastasis to bone marrow is a single site of involvement.NAACCR Item
NAACCR #960| Clinical M | Clinical M Display | Description | Registrar Notes |
|---|---|---|---|
| c0 | cM0 | No distant metastasis | Unknown; distant metastasis not stated Distant metastasis cannot be assessed Not documented in patient record |
| c1 | cM1 | Distant metastasis | CLINICAL assessment only: Note: M1 has subcategories of M1a, M1b, M1c, M1d and M1e. Assign M1 only when there is no information available to assign one of the subcategories Distant metastasis WITH or WITHOUT distant lymph nodes Distant metastasis, NOS Stated as M1[NOS] |
| c1A | cM1a | Not defined by UICC* | CLINICAL assessment only: Single metastasis to sites other than CNS Stated as M1a |
| c1B | cM1b | Not defined by UICC* | CLINICAL assessment only: Multiple metastasis to sites other than CNS Stated as M1b |
| c1C | cM1c | Not defined by UICC* | CLINICAL assessment only: CNS metastasis CNS location not specified Stated as M1c |
| c1D | cM1d | Not defined by UICC* | CLINICAL assessment only: Discrete mass(es) with leptomeningeal and/or CSF involvement Postchiasmatic lesions Stated as M1d |
| c1E | cM1e | Not defined by UICC* | CLINICAL assessment only: Leptomeningeal and/or Cerebral Spine Fluid (CSF) involvement Stated as M1e |
| p1 | pM1 | Distant metastasis | HISTOLOGICALLY confirmed: Note: M1 has subcategories of M1a, M1b, M1c, M1d and M1e. Assign M1 only when there is no information available to assign one of the subcategories Distant metastasis WITH or WITHOUT distant lymph nodes Distant metastasis, NOS |
| p1A | pM1a | Single metastasis to sites other than CNS | HISTOLOGICALLY confirmed |
| p1B | pM1b | Multiple metastasis to sites other than CNS | HISTOLOGICALLY confirmed |
| p1C | pM1c | CNS metastasis | HISTOLOGICALLY confirmed: CNS location not specified |
| p1D | pM1d | Discrete mass(es) without leptomeningeal and/or CSF involvement | HISTOLOGICALLY confirmed: Postchiasmatic lesions |
| p1E | pM1e | Leptomeningeal and/or Cerebral Spine Fluid (CSF) involvement | HISTOLOGICALLY confirmed |
| 88 | 88 | Not applicable | Primary site/histology not TNM defined Death certificate only (DCO) case |
| <BLANK> | BLANK | See Registrar Notes | Clinical classification criteria not met Clinical classification criteria met, evaluation done: No information about diagnostic workup Results not documented in patient record Clinical evaluation of T and N not done, no evidence metastatic disease Tumor first detected on surgical resection (no clinical workup) Only Clinical Stage Group documented (no T, N, or M information available) |