Site-Specific Factor 9
PDGFRA Gene Mutation
Notes
**Note 1:** Some gastrointestinal stromal tumors (GISTs) have oncogenic mutations of the platelet-derived growth factor receptor alpha (PDGFRA) gene, located on chromosome 4q. This test is a special molecular diagnostic test performed on tumor tissue to identify PDGFRA mutations. Some GISTs that are negative for KIT mutations are positive for PDGFRA mutation. **Note 2:** Code the result of the PDGFRA gene test. Another name for PDGFRA is CD140A. **Note 3:** See **Site-Specific Factor 7, KIT Gene Immunohistochemistry (IHC)** and **Site Specific Factor 8, KIT Gene Mutations** for coding information about KIT gene expression and mutations.Default
988NAACCR Item
NAACCR #2863| Code | Description |
|---|---|
| 010 | PDGFRA gene test positive for mutations |
| 020 | PDGFRA gene test negative for mutations; no mutations; normal or wild-type gene |
| 988 | Not applicable: Information not collected for this case |
| 997 | Test ordered, results not in chart; results pending |
| 998 | Test not done (test not ordered and not performed) |
| 999 | Unknown or no information Not documented in patient record |