Site-Specific Factor 18
Disseminated Tumor Cells (DTC) and Method of Detection
Notes
**Note 1:** Disseminated tumor cells (DTCs) are isolated tumor cells (ITCs) (micrometastases less than or equal to 0.2 mm) found in the bone marrow or other nonregional nodal tissues or organs. **Note 2:** Immunohistochemistry (IHC) with cytokeratin stains and Reverse Transcription Polymerase Chain Reaction (RT-PCR) are laboratory methods for identifying very small amounts of tumor cells in tissue. RT-PCR amplifies genetic material identified by probes for tumor genes to a detectable level. **Note 3:** Any positive test takes precedence over a negative or borderline test. Information about a known test takes precedence over no information about other tests.Default
988NAACCR Item
NAACCR #2872| Code | Description |
|---|---|
| 010 | Positive, Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) test |
| 020 | Positive, immunohistochemistry (IHC) test |
| 025 | Positive on RT-PCR and IHC |
| 030 | Positive, other test type |
| 040 | Positive, unknown test type |
| 110 | Negative/normal, RT-PCR test |
| 120 | Negative/normal IHC test |
| 130 | Negative/normal, other test type |
| 140 | Negative/normal, unknown test type |
| 210 | Borderline; equivocal; indeterminate; undetermined if positive or negative, RT-PCR test |
| 220 | Borderline; equivocal; indeterminate; undetermined if positive or negative, IHC test |
| 230 | Borderline; equivocal; indeterminate; undetermined if positive or negative, other test type |
| 240 | Borderline; equivocal; indeterminate; undetermined if positive or negative, unknown test type |
| 988 | Not applicable: Information not collected for this case |
| 997 | Test ordered, results not in chart |
| 998 | Test not done (test not ordered and not performed) |
| 999 | Unknown or no information Not documented in patient record |