Site-Specific Factor 6
Chromosome 19q: Loss of Heterozygosity (LOH)
Notes
**Note 1:** This is a special molecular diagnostic test performed on tumor tissue to identify loss of genetic material normally found on the long arm of one of the patient's two copies of chromosome 19. A normal cell will contain two complete copies of each chromosome, one from each parent, and this normal state is termed heterozygous. Loss of heterozygosity (LOH) is an abnormal state reflecting damage to the chromosome. **Note 2:** Other terms for LOH include gene deletion and allelic loss. **Note 3:** For brain tumors, tests for LOH of chromosomes 1p and 19q may be performed at the same time and reported on a single report. See also Site-Specific Factor 5.Default
988NAACCR Item
NAACCR #2930Metadata
None| Code | Description |
|---|---|
| 010 | Test positive for loss of heterozygosity (LOH) |
| 020 | Test negative for LOH |
| 988 | Not applicable: Information not collected for this case |
| 997 | Test ordered, results not in chart |
| 998 | No histologic examination of primary site Test not done (test not ordered and not performed) |
| 999 | Unknown or no information Not documented in patient record |