Neuroblastoma

Primary Site Histology Behavior
C000-C809 9490, 9500 3

Notes

9490, 9500: C000-C809 (all ages) **Note 1:** The following sources were used in the development of this schema * [Toronto Childhood Cancer Stage Guidelines, Version 2, May 2022](https://cancerqld.blob.core.windows.net/content/docs/childhood-cancer-staging-for-population-registries.pdf) * [Children’s Oncology Group - Newly Diagnosed with Neuroblastoma](https://childrensoncologygroup.org/newly-diagnosed-with-neuroblastoma) * [SEER Extent of Disease (EOD) 2018: Codes and Coding Instructions](https://seer.cancer.gov/tools/staging/eod/2018_Extent_of_Disease_General_Instructions.pdf) * [Summary Stage 2018 - SEER (cancer.gov)](https://seer.cancer.gov/tools/ssm/) **Note 2:** For Neuroblastoma, there are two different staging systems collected. * Toronto Staging uses the *International Neuroblastoma Risk Group Staging System (INRGSS)* and records the stage group only. This is a clinical evaluation only based on image defined risk factors. This information will be collected in 1185: Intl Neuroblastoma Risk Gp Stag Sys * The Children’s Oncology Group (COG) use the *International Neuroblastoma Staging System (INSS)*, which is based on surgical resection and is defined by stage group * Pediatric Primary Tumor, Pediatric Regional Nodes, and Pediatric Mets will be collected for surveillance purposes based on surgical resection and will derive the INSS Stage Group

Data Items

Name Default Value Used for Staging NAACCR Item Required By Metadata
Year of Diagnosis <BLANK> No NAACCR #390
dateOfDiagnosis
None None
Primary Site <BLANK> Yes NAACCR #400
primarySite
All None
Histology <BLANK> Yes NAACCR #522
histologicTypeIcdO3
All None
Behavior <BLANK> Yes NAACCR #523
behaviorCodeIcdO3
All None
Age at Diagnosis <BLANK> Yes NAACCR #230
ageAtDiagnosis
All None
Pediatric Primary Tumor 999 Yes NAACCR #1136
pediatricPrimaryTumor
All None
Pediatric Regional Nodes 999 Yes NAACCR #1137
pediatricRegionalNodes
All None
Pediatric Mets 99 Yes NAACCR #1138
pediatricMets
All None
Intl Neuroblastoma Risk Grp Stag Sys (INRGSS) <BLANK> Yes NAACCR #1185
inrgss
All SSDI
Intl Neuroblastoma Path Prog Class (INPC) <BLANK> No NAACCR #1187
inpc
SEER SSDI
n-MYC Amplification <BLANK> No NAACCR #1186
nMycAmplification
SEER SSDI

Initial Context

Staging Methods

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Pediatric Stage

Start

Additional Context
toronto_stage_group = 90
pediatric_group = 90

Next Step

  1. Pediatric Stage
  2. pediatric_group

Next Step

  1. Toronto Stage
  2. toronto_stage_group

End

Outputs

Name Default Value Description NAACCR Item Metadata
Pediatric ID 4a NAACCR #1132
pediatricId
None
Toronto Version Number 2 Version of the Toronto Pediatric Staging System that this version of the Pediatric staging API is based upon. NAACCR #1135
torontoVersionNumber
None
Derived Version {{ctx_alg_version}} For Pediatric ID Version Current - 1133, update all cases when API is updated; Pediatric ID Version Original - 1134, set when the case is coded and do not update None None
Derived Pediatric T 88 NAACCR #1142
derivedPediatricT
None
Derived Pediatric N 88 NAACCR #1143
derivedPediatricN
None
Derived Pediatric M 88 NAACCR #1144
derivedPediatricM
None
Derived Pediatric Stage Group <BLANK> NAACCR #1145
derivedPediatricStageGroup
None
Toronto T N/A NAACCR #1146
torontoT
None
Toronto N N/A NAACCR #1147
torontoN
None
Toronto M N/A NAACCR #1148
torontoM
None
Toronto Stage Group <BLANK> NAACCR #1149
torontoStageGroup
None