NAACCR Item #3918: Profound Immune Suppression

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,918 1 NAACCR 2018 18

NAACCR XML: Tumor.profoundImmuneSuppression


Profound Immune Suppression, suppressed immune status that may be associated with HIV/AIDs, solid organ transplant, chronic lymphocytic leukemia, non-Hodgkin lymphoma, multiple conditions or other conditions, increases the risk of developing Merkel Cell Carcinoma and is an adverse prognostic factor.


Profound Immune Suppression is a Registry Data Collection Variable in AJCC. It was previously collected as Merkel Cell Penis, SSF #22, Merkel Cell Scrotum SSF #22, Merkel Cell Skin, SSF# 22, and Merkel Cell Vulva, SSF# 22.


0No immune suppression condition(s) identified/not present
1Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS)
2Solid organ transplant recipient
3Chronic lymphocytic leukemia
4Non-Hodgkin lymphoma
5Multiple immune suppression conditions
6Profound immune suppression present
8Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code 8 may result in an edit error.)
9Not documented in medical record Profound immune suppression not assessed or unknown if assessed

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.