NAACCR Item #3909: Perineural Invasion

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,909 1 NAACCR 2018 18

NAACCR XML: Tumor.perineuralInvasion


Perineural Invasion, within or adjacent to the primary tumor, is a negative prognostic factor for cutaneous squamous cell carcinomas of the head and neck and carcinomas of the colon and rectum, eyelid and lacrimal gland.


Perineural Invasion is a Registry Data Collection Variable in AJCC. It was previously collected as Colon and Rectum CS SSF# 8 and Lacrimal Gland CS SSF# 4.


0Perineural invasion not identified/not present
1Perineural invasion identified/present
8Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code 8 may result in an edit error.)
9Not documented in medical record Pathology report does not mention perineural invasion Cannot be determined by the pathologist Perineural invasion not assessed or unknown if assessed

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.