NAACCR Item #3832: Extranodal Extension Head and Neck Pathological

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,832 3 NAACCR 2018 18

NAACCR XML: Tumor.extranodalExtensionHeadNeckPath


Extranodal extension (ENE) is defined as "the extension of a nodal metastasis through the lymph node capsule into adjacent tissue" and is a prognostic factor for most head and neck tumors. This data item pertains to pathological staging extension.


Extranodal Extension Head and Neck Pathological is a Registry Data Collection Variable in AJCC. It was previously collected as Head and Neck SSF# 9 (Common SSF).


0.0Lymph nodes positive for cancer but ENE not identified or negative
0.1-9.9ENE 0.1 to 9.9 mm
X.1ENE 10 mm or greater
X.2ENE microscopic, size unknown Stated as ENE (mi)
X.3ENE major, size unknown Stated as ENE (ma)
X.4ENE present, microscopic or major unknown, size unknown
X.7Surgically resected regional lymph nodes negative for cancer (pN0)
X.8Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code X.8 may result in an edit error)
X.9Not documented in medical record No surgical resection of regional lymph nodes ENE not assessed pathologically, or unknown if assessed Pathological assessment of lymph nodes not done, or unknown if done

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.