NAACCR Item #3923: S Category Clinical

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,923 1 NAACCR 2018 18

NAACCR XML: Tumor.sCategoryClinical


S Category Clinical combines the results of pre-orchiectomy Alpha Fetoprotein (AFP), Human Chorionic Gonadotropin (hCG) and Lactate Dehydrogenase (LDH) into a summary S value.


S Category Clinical is required for prognostic stage grouping in AJCC 8th edition, Chapter 59 Testis. It is a new data item for cases diagnosed 1/1/2018+.


0S0: Marker study levels within normal levels
1S1: At least one of these values is elevated AND LDH less than 1.5 x N\* AND hCG (mIU/L) less than 5,000 AND AFP (ng/mL) less than 1,000
2S2: LDH 1.5 x N\* to 10 x N\* OR hCG (mIU/L) 5,000 to 50,000 OR AFP (ng/mL) 1,000 to 10,000
3S3: Only one elevated test is needed LDH greater than 10 x N\* OR hcG (mIU/mL) greater than 50,000 OR AFP (ng/mL) greater than 10,000
9SX: Not documented in medical record S Category Clinical not assessed or unknown if assessed

*N indicates the upper limit of normal for the LDH assay.
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.