NAACCR Item #3855: HER2 Overall Summary

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,855 1 NAACCR 2018 18

NAACCR XML: Tumor.her2OverallSummary


HER2 Overall Summary is a summary of results from HER2 testing.


This data item is required for prognostic stage grouping in AJCC 8th edition, Chapter 48, Breast. It was previously collected as Breast, CS SSF # 15.Experts recommend that every invasive breast cancer be tested for the presence of HER2 because anti-HER2 treatments are highly effective for these tumors.
HER2 overall summary will be collected for Esophagus and Esophagogastric Junction and Stomach for cases diagnosed 1/1/21+ because NCCN guidelines recommend HER2 testing at time of diagnosis if patients are documented or suspected of having metastatic disease. HER2 monoclonal antibodies may be added to chemotherapy for patients with HER2 positive disease.


0HER2 negative; equivocal
1HER2 positive
7Test ordered, results not in chart
8Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code 8 will result in an edit error.)
9Not documented in medical record Cannot be determined (indeterminate) HER2 Overall Summary status not assessed or unknown if assessed

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.