NAACCR Item #3802: Chromosome 19q: Loss of Heterozygosity (LOH)

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,802 1 NAACCR 2018 18

NAACCR XML: Tumor.chromosome19qLossHeterozygosity


Chromosome 19q: Loss of Heterozygosity (LOH) refers to the loss of genetic material normally found on the long arm of one of the patient's two copies of chromosome 19. Codeletion of Chromosome 1p and 19q is a diagnostic, prognostic and predictive marker for gliomas and is strongly associated with the oligodendroglioma phenotype.


Chromosome 19q: Loss of Heterozygosity (LOH) is a Registry Data Collection Variable in AJCC. It was previously collected as Brain, CS SSF #6.


0Chromosome 19q deletion/LOH not identified/not present
1Chromosome 19q deletion/LOH present
6Benign or borderline tumor
7Test ordered, results not in chart
8Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code 8 will result in an edit error.)
9Not documented in patient record Cannot be determined by the pathologist Chromosome 19q: LOH not assessed or unknown if assessed

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.