NAACCR Item #3931: Serum Beta-2 Microglobulin Pretreatment Level

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Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired Column #
3931 1 NAACCR 2018 18 1918 - 1918

NAACCR XML: Tumor.serumBeta2MicroglobulinPretxLvl

Serum Beta-2 Microglobulin is a protein that is found on the surface of many cells and plentiful on the surface of white blood cells. Increased production or destruction of these cells causes Serum β2 (beta-2) Microglobulin level to increase. Elevated Serum β2 (beta-2) Microglobulin level is a prognostic factor for plasma cell myeloma.
Serum Beta-2 Microglobulin Pretreatment Level is a prognostic factor required in AJCC 8th edition, Chapter 82 Plasma Cell Myeloma and Plasma Cell Disorders, for staging of plasma cell myeloma. It is a new data item for cases diagnosed 1/1/2018+.
0 ß2-microglobulin <3.5 mg/L
1 ß2-microglobulin =3.5 mg/L <5.5 mg/L
2 ß2-microglobulin =5.5 mg/L
7 Test ordered, results not in chart
9 Not documented in medical record

Serum Beta-2 Microglobulin Pretreatment Level not assessed or unknown if assessed
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.