NAACCR Item #3924: S Category Pathological

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3924 1 NAACCR 2018 18

NAACCR XML: Tumor.sCategoryPathological

S Category Pathological combines the results of post-orchiectomy Alpha Fetoprotein (AFP), Human Chorionic Gonadotropin (hCG) and Lactate Dehydrogenase (LDH) into a summary S value.
S Category Pathological is required for prognostic stage grouping in AJCC 8th edition, Chapter 59, Testis. It is a new data item for cases diagnosed 1/1/2018+.
0S0: Marker study levels within normal levels
1S1: At least one of these values is elevated AND
LDH less than 1.5 x N* AND
hCG (mIU/L) less than 5,000 AND
AFP (ng/mL) less than 1,000
LDH 1.5 x N* to 10 x N* OR
hCG (mIU/L) 5,000 to 50,000 OR
AFP (ng/mL) 1,000 to 10,000
3S3: Only one elevated test is needed
LDH greater than 10 x N* OR
hcG (mIU/mL) greater than 50,000 OR
AFP (ng/mL) greater than 10,000
5Post orchiectomy serum tumor markers unknown or not done but pre orchiectomy serum tumor markers were normal
9SX: Not documented in medical record
S Category Pathological not assessed or unknown if assessed
*N indicates the upper limit of normal for the LDH assay.
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.