NAACCR Item #3852: HER2 ISH Dual Probe Ratio

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,852 4 NAACCR 2018 18

NAACCR XML: Tumor.her2IshDualProbeRatio


HER2 in situ hybridization (ISH) Dual Probe Ratio is the summary score for HER2 testing using a dual probe. The test will report results for both HER2 and CEP17, the latter used as a control. The HER2/CEP17 ratio is reported.


HER2 ISH Dual Probe Ratio is a Registry Data Collection Variable in AJCC. It is a new data item for cases diagnosed 1/1/2018+.


0.0-99.9Ratio of 0.0 to 99.9
XX.2Less than 2.0
XX.3Greater than or equal to 2.0
XX.7Test ordered, results not in chart
XX.8Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code XX.8 will result in an edit error.)
XX.9Not documented in medical record Results cannot be determined (indeterminate) Dual probe test not done; only single probe test performed HER2 ISH Dual Probe Ratio not assessed or unknown if assessed

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.