NAACCR Item #3869: LDH Level

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,869 1 NAACCR

NAACCR XML: Tumor.ldhPretreatmentLevel


LDH (Lactate Dehydrogenase) is an enzyme involved in conversion of sugars to energy and present in most cells in the body. Elevated pretreatment LDH is an adverse prognostic factor for plasma cell myeloma and melanoma of the skin.


LDH (Lactate Dehydrogenase) Level is a prognostic factor required in AJCC 8^th^ edition for Chapter 83 Plasma Cell Myeloma and Plasma Cell Disorders and Chapter 47 Melanoma Skin. For Plasma Cell Myeloma, LDH is part of the RISS Stage and is new for cases diagnosed 1/1/2018+. For Melanoma Skin, LDH is used to define the M subcategories and was previously collected as LDH Pretreatment Level and Melanoma Skin, SSF #4.


0Normal LDH level Low, below normal
1Above normal LDH level; High
5Schema Discriminator 1: Plasma Cell Myeloma Terminology coded to 1 or 9
7Test ordered, results not in chart
9Not documented in medical record LDH (Lactate Dehydrogenase) Pretreatment Level not assessed or unknown if assessed

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.