NAACCR Item #3854: HER2 ISH Summary

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3,854 1 NAACCR 2018 18

NAACCR XML: Tumor.her2IshSummary


HER2 in situ hybridization (ISH) Summary is the summary score for results of testing for ERBB2 gene copy number by any ISH method. An immunohistochemistry (IHC) test identifies the protein expressed by the gene (ERBB2), and an ISH test identifies the number of copies of the gene (ERBB2) itself.


HER2 ISH Summary is a Registry Data Collection Variable in AJCC. It is a new data item for cases diagnosed 1/1/2018+.


0Negative [not amplified]
3Positive [amplified]
7Test ordered, results not in chart
8Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code 8 will result in an edit error.)
9Not documented in medical record Results cannot be determined (indeterminate) HER2 ISH Summary not assessed or unknown if assessed

Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.