NAACCR Item #3816: Brain Molecular Markers

Item # Length Source of Standard Year Implemented Version Implemented Year Retired Version Retired
3816 2 NAACCR 2018 18

NAACCR XML: Tumor.brainMolecularMarkers

Multiple brain molecular markers have become standard pathology components necessary for diagnosis. This data item captures clinically important brain cancer subtypes identified by molecular markers that are not distinguishable by ICD-O-3 codes.
Collection of these clinically important brain cancer subtypes has been recommended by CBTRUS.
01 Diffuse astrocytoma, IDH-mutant (9400/3)
02 Diffuse astrocytoma, IDH-wildtype (9400/3)
03 Anaplastic astrocytoma, IDH-mutant (9401/3)
04 Anaplastic astrocytoma, IDH-wildtype (9401/3)
05 Glioblastoma, IDH-wildtype (9440/3)
06 Oligodendroglioma, IDH-mutant and 1 p/19q co-deleted (9450/3)
07 Anaplastic oligodendroglioma, IDH-mutant and 1 p/19q co-deleted (9451/3)
08 Medulloblastoma, SHH-activated and TP53-wildtype (9471/3)
09 Embryonal tumor with multilayered rosettes, C19MC-altered (9478/3)
85 Not applicable: Histology not 9400/3, 9401/3, 9440/3, 9450/3, 9451/3, 9471/3, 9478/3
86 Benign or borderline tumor
87 Test ordered, results not in chart
88 Not applicable: Information not collected for this case
(If this item is required by your standard setter, use of code 88 will result in an edit error.)
99 Not documented in patient record
No microscopic confirmation
Brain molecular markers not assessed or unknown if assessed
Each Site-Specific Data Item (SSDI) applies only to selected primary sites, histologies, and years of diagnosis. Depending on applicability and standard-setter requirements, SSDIs may be left blank.