EOD Primary Tumor

Notes

**Note 1:** **Common histology** * Over 90% of penile cancers are squamous cell carcinomas arising in the skin. * Other cancers arising in the skin include adenocarcinomas (5%) arising in sweat glands, melanomas (2%, included in the Melanoma schema), and basal cell carcinoma (2%). About 1% of penile cancers are sarcomas, arising in subcutaneous connective tissues. **Note 2:** **Verrucous carcinoma** * If verrucous carcinoma (8051/3) is described as noninvasive or as having a broad pushing border or penetration, assign code 050. * If verrucous carcinoma is not so characterized, assign code 070, Verrucous carcinoma, NOS. * If there is destructive invasion of verrucous carcinoma into structures in code 100 or greater, assign the appropriate higher code. **Note 3:** **Limited to the penis** * Tumors limited to the penis (see codes 100, 200, 300) include * Dartos fascia (foreskin) * Dermis (foreskin) * Lamina propria (glans and foreskin) * Subepithelial connective tissue (shaft)
Code Description SS2018 T
000 In situ, intraepidermal, intraepithelial, noninvasive Bowen disease Carcinoma in situ (Penile intraepithelial neoplasia III [PeIN III]) Erythroplasia of Queyrat IS
050 Noninvasive localized squamous cell carcinoma Noninvasive verrucous carcinoma IS
070 Verrucous carcinoma, NOS (ICD-O-3 code 8051/3 only) L
100 Limited to penis * WITHOUT perineural and/or lymphovascular invasion * WITH low grade (i.e., grade 1-2) or UNKNOWN grade L
150 Code 100 WITH high grade (i.e., grade 3 or sarcomatoid) L
200 Limited to penis * WITH perineural and/or lymphovascular invasion * WITH or WITHOUT high grade (i.e., grade 3 or sarcomatoid) L
300 Limited to penis * UNKNOWN perineural and/or lymphovascular invasion Confined to penis, NOS Localized, NOS L
400 Corpus spongiosum (including tunica albuginea) * WITHOUT urethral invasion or UNKNOWN if urethral invasion RE
450 Code 400 WITH urethral invasion RE
500 Corpus cavernosum (including tunica albuginea) * WITHOUT urethral invasion OR UNKNOWN if urethral invasion RE
550 Code 500 WITH urethral invasion RE
600 Muscle, NOS * Bulbospongiosus * Ischiocavernosus * Superficial transverse perineal Prostate Pubic bone Scrotum Skin (abdominal, perineum) RE
700 Further contiguous extension * Testis D
800 No evidence of primary tumor U
999 Unknown extension Primary tumor cannot be assessed Not documented in medical record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) Pettaway, C.A., Srigley, J.R., Amin, M.B., et al. **Penis**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017